YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: unc-129
Organism: Caenorhabditis elegans
Length: 407 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-129.

Description E-value Query
Range
Subject
Range
gi|45361239, gi|... - gi|45361239|ref|NP_989197.1| bone morphogenetic protein 7, gene 1 [Xenopus (Silurana) tropicalis], g...
263.0 [0..21] [406..45]

Back

Predicted Domain #1
Region A:
Residues: [1-67]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRLPIVLLL SVFSIANCAK VDVDLINETI RDLLHFKSSD PNVTSFHRSS HTLTEHMKNL  60
   61 YENFIDE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [68-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSNEDGNLVR AIEPAVGKFE GQEVLVFDVE GFDSHESIMR AELHFYLRRR DSFARRRSRQ  60
   61 IRAKSVCVNE YCRQQTLKKI RVGGDENLEE YKVIWDATKS VFDSYHLDAK QAVFRITREH 120
  121 SKMRPYAEMI R

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [199-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSTPFLVIYS KVNHTLDTVS VMKQTEQTKR KRRDLGNEEL REYYNYNSIP LDNDDREPIK  60
   61 RKNGKKNSLS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [269-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEISSEDVWQ GFGEETSREE RERIANEELA NDVRVVLLQN KNRCHKEGVL VSLKHFGWDR  60
   61 YVIEPKTIET SFCKGKCAKP MLTSGKASNH AMLQSLFAAE PVCCAPTNLK SLNFWYRDEK 120
  121 GRTVIRNYSK MLIGSCSCL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.69897
Match: 1bmpA
Description: BONE MORPHOGENETIC PROTEIN-7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.69992067408072 bayes_pls_golite062009
receptor binding 2.08021343073973 bayes_pls_golite062009
binding 1.94128368349087 bayes_pls_golite062009
receptor serine/threonine kinase binding 1.36183834539535 bayes_pls_golite062009
transforming growth factor beta receptor binding 1.15487182590328 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding 1.15487182590328 bayes_pls_golite062009
protein dimerization activity 0.803483953206309 bayes_pls_golite062009
growth factor activity 0.61315906855544 bayes_pls_golite062009
protein homodimerization activity 0.50995657444857 bayes_pls_golite062009
vascular endothelial growth factor receptor binding 0.495685919978181 bayes_pls_golite062009
identical protein binding 0.46701037831689 bayes_pls_golite062009
growth factor binding 0.115424337995679 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle