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View Structure Prediction Details

Protein: CE23773
Organism: Caenorhabditis elegans
Length: 746 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE23773.

Description E-value Query
Range		 Subject
Range
CE39813 - status:Predicted UniProt:Q966D8 protein_id:AAK68410.3
 257.0 [0..1] [746..1]

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Predicted Domain #1
Region A:
Residues: [1-319] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFDYKVHST LPHIPKTPSF AFWNRTRIYI MVLTLACLTF IQINTVIFNF TVICMEDIVE  60
   61 DYNLLTNYTG TPSTKALALS PTAHCSRRCA GPRVTTAVVG GRGTRGVRVS HFGTHWFQRT 120
  121 TEKSLLFSGA AIGGLIGLIP SVPLINSIGL RNFQTISGLI SALGALLFPL AVSIDFYSSF 180
  181 LCRVLQGMGS SIIFTSVGVV PGVWAPSNET NTFTAILSCA LQLGNIICMP VSGFLCESSL 240
  241 GWRSIYYLFG GLTAIIFIMF WFTYTDDPKL HRLTEIQILK IHFFGKNVSE NCEVHPTTSD 300
  301 GRLPKIRKTS SFVFWNKTR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.05
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.17122575244927 bayes_pls_golite062009
ion transmembrane transporter activity 4.40082803797762 bayes_pls_golite062009
cation transmembrane transporter activity 4.15136138921997 bayes_pls_golite062009
transporter activity 3.82096685159505 bayes_pls_golite062009
anion transmembrane transporter activity 3.72315344358443 bayes_pls_golite062009
transmembrane transporter activity 3.34396155292818 bayes_pls_golite062009
substrate-specific transporter activity 3.32643461660963 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 2.38147400623282 bayes_pls_golite062009
phosphate transmembrane transporter activity 1.55146182911318 bayes_pls_golite062009
active transmembrane transporter activity 1.46819549608723 bayes_pls_golite062009
binding 1.278768212932 bayes_pls_golite062009
secondary active transmembrane transporter activity 0.869150152038001 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.339747214378126 bayes_pls_golite062009
polyol transmembrane transporter activity 0.339747214378126 bayes_pls_golite062009
solute:cation symporter activity 0.327558013224678 bayes_pls_golite062009
symporter activity 0.327558013224678 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.222664452597504 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [320-746] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFIMILTLAC LTFIQINTLL FNFTVICMED VVENYNLLTN YTATHWFQRN TEKSLLFSGV  60
   61 AIGGLIGLIP SVPLINALGL RNVQTISGLI SAFGALLFPL AVSIGFYTTL LCRILQGMGS 120
  121 AVMFTSVGVV PNVWAPRNEA NTFMAILSCA LQLSNIICMP VSGLLCESAL GWRSIYYLFG 180
  181 GLTFIMFIVF WISYKDDPKM YRKRNLKKSP AAKLSRYLAI CTDPTVLITW ITCFGGFVGL 240
  241 YSLSLYGPTY LREILKFDVR ETGFLSALPF ILSAIIKFAA GKISDKLSFL SEKSRFVFFA 300
  301 ATSQIGFVAG LLVMAFTTNR LIAQIAFNFA IVSSGMNVMG VFKVVQLRCL QHVHFAIAVI 360
  361 SFTTYLVQFL APVIVGIICP DNTPAQWTTL FLVISAIIIV CTVGFPFLTK SDAADYTKKK 420
  421 TVESCRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.045757
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
cation transmembrane transporter activity 4.31967711223954 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.94605227012838 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 2.52916479889426 bayes_pls_golite062009
phosphate transmembrane transporter activity 1.78662033436109 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.26757615356623 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle