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View Structure Prediction Details

Protein: prmt-1
Organism: Caenorhabditis elegans
Length: 348 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prmt-1.

Description E-value Query
Range		 Subject
Range
gi|54638834, gi|... - gi|54638834|gb|EAL28236.1| GA19682-PA [Drosophila pseudoobscura], gi|125775876|ref|XP_001359093.1| G...
 299.0 [0..6] [347..35]

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Predicted Domain #1
Region A:
Residues: [1-348] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTENGKSAD APVAAPAAKE LTSKDYYFDS YAHFGIHEEM LKDEVRTTTY RNSIYHNSHL  60
   61 FKDKVVMDVG SGTGILSMFA AKAGAKKVFA MEFSNMALTS RKIIADNNLD HIVEVIQAKV 120
  121 EDVHELPGGI EKVDIIISEW MGYCLFYESM LNTVLVARDR WLAPNGMLFP DKARLYVCAI 180
  181 EDRQYKEDKI HWWDSVYGFN MSAIKNVAIK EPLVDIVDNA QVNTNNCLLK DVDLYTVKIE 240
  241 DLTFKSDFKL RCTRSDYIQA FVTFFTVEFS KCHKKTGFST GPDVQYTHWK QTVFYLKDAL 300
  301 TVKKGEEITG SFEMAPNKNN ERDLDINISF DFKGEVCDLN EQNTYTMH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.045757
Match: 1or8A
Description: Structure of the Predominant protein arginine methyltransferase PRMT1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein-arginine N-methyltransferase activity 5.52520020727046 bayes_pls_golite062009
arginine N-methyltransferase activity 5.52520020727046 bayes_pls_golite062009
protein methyltransferase activity 5.03267617653315 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 4.4632173842967 bayes_pls_golite062009
histone methyltransferase activity 4.40911163698179 bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity 4.39379274790202 bayes_pls_golite062009
methyltransferase activity 4.15445027778357 bayes_pls_golite062009
N-methyltransferase activity 4.07806017452628 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 4.07153733729662 bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity 3.55785970363721 bayes_pls_golite062009
transferase activity 2.926540904444 bayes_pls_golite062009
histone-arginine N-methyltransferase activity 2.86617323549909 bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific) 2.25250509433971 bayes_pls_golite062009
DNA-methyltransferase activity 2.18991764495147 bayes_pls_golite062009
[myelin basic protein]-arginine N-methyltransferase activity 1.7438509457599 bayes_pls_golite062009
histone methyltransferase activity (H3-R2 specific) 1.49229188826344 bayes_pls_golite062009
histone methyltransferase activity (H2A-R3 specific) 1.49229188826344 bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity 1.48228631448092 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
signal transducer activity 1.11388181877851 bayes_pls_golite062009
molecular transducer activity 1.11388181877851 bayes_pls_golite062009
binding 0.976078016260105 bayes_pls_golite062009
histone binding 0.964746527369069 bayes_pls_golite062009
lysine N-methyltransferase activity 0.858129308056814 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 0.858129308056814 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 0.858129308056814 bayes_pls_golite062009
RNA methyltransferase activity 0.817509452491588 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 0.703178429468566 bayes_pls_golite062009
transcription regulator activity 0.237494224321778 bayes_pls_golite062009
rRNA methyltransferase activity 0.230719796976667 bayes_pls_golite062009
DNA binding 0.22268909330347 bayes_pls_golite062009
nucleic acid binding 0.103639608104023 bayes_pls_golite062009
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