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View Structure Prediction Details

Protein: ftn-2
Organism: Caenorhabditis elegans
Length: 170 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ftn-2.

Description E-value Query
Range
Subject
Range
gi|47125326 - gi|47125326|gb|AAH70494.1| FTH1 protein [Homo sapiens]
240.0 [0..2] [170..56]
gi|114637918 - gi|114637918|ref|XP_001140124.1| PREDICTED: similar to Ferritin heavy chain (Ferritin H subunit) (Pr...
240.0 [0..2] [170..114]
gi|83404987 - gi|83404987|gb|AAI11079.1| Fth1 protein [Rattus norvegicus]
236.0 [0..2] [169..57]
gi|109078314 - gi|109078314|ref|XP_001088733.1| PREDICTED: similar to mitochondrial ferritin [Macaca mulatta]
224.0 [0..2] [170..67]
gi|28630234 - gi|28630234|gb|AAN63032.1| ferritin heavy chain polypeptide 1 [Branchiostoma lanceolatum]
223.0 [0..1] [170..2]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLARQNYHS EVEAAVNKQI NIELYASYVY LSMSFYFDRD DVALPNIAKF FKEQSDEERE  60
   61 HATELMRVQN LRGGRVVLQD IQKPENDEWG TALKAFEAAL ALEKFNNESL LKLHSTAGNH 120
  121 NDAHLTDFIE EKYLDEQVKS INEFARMVAN LKRVGPGVGE YVFDKEHFSD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.69897
Match: 1fhaA
Description: SOLVING THE STRUCTURE OF HUMAN H FERRITIN BY GENETICALLY ENGINEERING INTERMOLECULAR CRYSTAL CONTACTS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ferric iron binding 5.55100638826026 bayes_pls_golite062009
iron ion binding 3.10225782829614 bayes_pls_golite062009
binding 1.95813969002966 bayes_pls_golite062009
transition metal ion binding 1.70242943635222 bayes_pls_golite062009
cation binding 1.66873432300081 bayes_pls_golite062009
metal ion binding 1.66873432300081 bayes_pls_golite062009
ion binding 1.66140448750278 bayes_pls_golite062009
ribonucleoside-diphosphate reductase activity 0.366005079572569 bayes_pls_golite062009
protein binding 0.30514049100341 bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor 0.289628933165632 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle