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View Structure Prediction Details

Protein: CE20170
Organism: Caenorhabditis elegans
Length: 783 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE20170.

Description E-value Query
Range
Subject
Range
gi|82973377, gi|... - gi|94401507|ref|XP_986813.1| PREDICTED: similar to Synaptojanin-1 (Synaptic inositol-1,4,5-trisphosp...
670.0 [0..7] [783..161]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIYTTPTAL ILEEQGERVE FDRRNGKVLE KPEESLEILD QDVVLCGNVE FLIGKISFDE  60
   61 QHFLFFVVDS SVVACYRGTS AESSHSIRRI ERVIAINVKS DGSVIKSQIT PGSGTKLKQG 120
  121 TEKIMKFFAE KVTKAEPRPA LLDDVLKLFN DSKDFYFCRS RDVTISSQKY FEKREAHT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [179-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEDSFFWNKR MVGNLGEAKI SDKFTCPIMQ GYVATSQLEI TDQINAYLTI TIISRRSTRR  60
   61 AGARYLRRGI DEASNVANFV ETELILNIFE HELSFVQCRG SIPVFWSQRG FKYRPPLIIN 120
  121 RSVEETHGVF TEHFKRLKAH YDTPLVAVS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [328-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVDQRGRELP LAQRFLEHCV KADDNDVTFF SFDLHQHCRG LNFQKLQTLI SSMEETLKTI  60
   61 GFCWVDKTGE VVQSQKGVVR TNCIDCLDRT NLVQGQISLF VVLQQAQRLG IFGPLCEPPE 120
  121 VLVQTMQTMW ADNGDVISTQ YAGTAALKGD VTRNGERKLM GVMKDGYNSA SRYYLTHTKD 180
  181 AQRQKAINIV TGQTEADENA EEEENE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [534-783]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEEEENISRM VTETIQFLVP TQQTVIAGWG LINAFQSSDE IDTVVILTRS NLYIVTYEID  60
   61 GEKMTDVQIV ALEDINTIQT GTSGNNRQCA RLETLEGVFI WRPSTVRLFN NTAIRLKSLE 120
  121 EANEYISSVA EQIQVGRNML TGAEGSVVPV AKITIPQMSV HRKSMAAMGA LFGKIKRVGK 180
  181 PSSLSKSAST ISTAQLPETD GNESDASQKS DHLMTKILKM SQFKSDSPQP EPFSSLLPAI 240
  241 SECQTKISLL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.0
Match: 1i9yA
Description: Synaptojanin, IPP5C domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 0.289377233792772 bayes_pls_golite062009
binding 0.207829503538562 bayes_pls_golite062009
catalytic activity 0.100726018663572 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.0232598567354486 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle