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View Structure Prediction Details

Protein: CE19788
Organism: Caenorhabditis elegans
Length: 442 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE19788.

Description E-value Query
Range
Subject
Range
gi|114554617 - gi|114554617|ref|XP_513189.2| PREDICTED: ephrin receptor EphB2 [Pan troglodytes]
348.0 [0..5] [442..517]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLTTLPPSQ LRPELEWLFP KEVTTSSSAI LKNKSAAEIP LNFLAEHSLA LIAALFLVVL  60
   61 TVALLAVLVQ YHCQKGTNSG GLGAGAISPK SFSTSPSQWT TCSTVSSTYS TQSLLQLIGS 120
  121 DLRQSLQGLL L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.0
Match: 1lckA
Description: p56-lck tyrosine kinase, SH3 domain; p56-lck tyrosine kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
molecular transducer activity 3.58651960433016 bayes_pls_golite062009
signal transducer activity 3.58651960433016 bayes_pls_golite062009
binding 3.12724619324809 bayes_pls_golite062009
epidermal growth factor receptor binding 2.9751846707539 bayes_pls_golite062009
insulin receptor binding 2.73485644242393 bayes_pls_golite062009
actin filament binding 2.59742039155224 bayes_pls_golite062009
cytoskeletal protein binding 2.21254869336424 bayes_pls_golite062009
protein binding 2.14586566310919 bayes_pls_golite062009
molecular adaptor activity 1.81145713371725 bayes_pls_golite062009
receptor binding 1.80554013976158 bayes_pls_golite062009
actin binding 1.79651396322487 bayes_pls_golite062009
vinculin binding 1.63216315345235 bayes_pls_golite062009
SH3/SH2 adaptor activity 1.59474164216385 bayes_pls_golite062009
protein kinase activity 1.4654611643382 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.39494498759145 bayes_pls_golite062009
transcription regulator activity 1.38649262176488 bayes_pls_golite062009
kinase activity 1.31102709888086 bayes_pls_golite062009
nucleic acid binding 1.28138694351561 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.27380124084989 bayes_pls_golite062009
DNA binding 1.17144894382542 bayes_pls_golite062009
transporter activity 0.896907103596953 bayes_pls_golite062009
protein binding, bridging 0.83823250804321 bayes_pls_golite062009
transmembrane transporter activity 0.713068405985864 bayes_pls_golite062009
protein complex binding 0.65988681496356 bayes_pls_golite062009
transcription factor activity 0.573315212617741 bayes_pls_golite062009
phosphoprotein binding 0.53070890116366 bayes_pls_golite062009
substrate-specific transporter activity 0.500685400112742 bayes_pls_golite062009
transferase activity 0.4880159130787 bayes_pls_golite062009
cytokine receptor binding 0.32837919709751 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.272368655500689 bayes_pls_golite062009
protein tyrosine kinase activity 0.206747304356052 bayes_pls_golite062009
insulin-like growth factor receptor binding 0.169458153875562 bayes_pls_golite062009
kinase binding 0.131981353175621 bayes_pls_golite062009
kinase regulator activity 0.10704587503284 bayes_pls_golite062009
receptor signaling protein activity 0.0443241110585009 bayes_pls_golite062009
ion transmembrane transporter activity 0.00318812576030902 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [132-442]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSEAVVLETI VGKGYFGNVY RGRMRDPAGR LIPVAVKTLK GERARDIAHI EKFLREGVVM  60
   61 KHLDHPHVLS LLGISISPAG NPWVVLPYME GGDLKTYIAD PNRALCVLEL LDFAHQVAQG 120
  121 MSYLAAQHFV HRDLAARNCM ISADRIVKVA DFGLAVDLLD KESYIDESET GPARLPLKWL 180
  181 APESLRDRRV FSSATDVWSF GVLMWELLTR AASPYGEVSN TKVRHYLETG MRLPQPTHCP 240
  241 DIIYDLMQCC WRSTPEDRPD FVFLSHRLRA LLQENTPDPF TRRVRPGAEQ FLLPVLPGRL 300
  301 FTNYFAAQMH S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.30103
Match: 2g15A
Description: No description for 2g15A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle