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View Structure Prediction Details

Protein: lea-1
Organism: Caenorhabditis elegans
Length: 733 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lea-1.

Description E-value Query
Range
Subject
Range
gi|7494117, gi|1... - pir||T30296 R27-2 protein - Trypanosoma cruzi, gi|1256742|gb|AAA96494.1| R27-2 protein [Trypanosoma...
259.0 [0..2] [733..299]

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Predicted Domain #1
Region A:
Residues: [1-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFMDKVKDT ANSAYESVEN TAVGAKDGVV GAFNTVGEKI GGAYDSTKQY ASDKVSAAGD  60
   61 YASEAGKKVG DAEDSMIQGA YDAKDSAKES ASNAGNKISN AFTSLKDSIT GDNAHKTGEA 120
  121 LNDNYESVKE SASEAADRLK EPAQNTADNA KDLANQTGEE MSDAFESVKQ LTSDTAENAK 180
  181 ENAHDAADTA KSYKDKAGEK ASGILDSFKA HASDAKDSVE NKASDAYNSA KDKAGDAWDS 240
  241 TKDAAGDAKD KTKSFTEKVG DKISGAYDSV KEKASDVADS FKAHSTDSKD NVENKAADAY 300
  301 NTAKDKASDA WDKTKDKAGE AKDKMGDAWD TTKDKAGDAW DTTKDKAGD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [350-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKGKAGDAWD TTKDKASDAW DTTKDKAGEA KDKMGEAWDH TKDKAGEAKD KASDAADDAQ  60
   61 GKSKSMTEKI GDSISGAWES TKDTAVSAKD KTAEAAGKVG DSISGAYDTV KEKASDIADS 120
  121 FKAHSTDSKD NVENKAADAY NSAKDKASDA WDKTKDKAGD AKDKAADAWD TTKDKAGDAW 180
  181 DSTKDHAADA KDKASDAAGD AKDKSKSLTE KA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [562-733]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDAISGAYDS VKEKASDIAD SFKAHSTNSK DNVENKASDA YNSAKDKASD AWDKTKDKAG  60
   61 EAKDKAGDAW DNTKDKAGNA WDSTKDKASD AWDTTKDKAS DAKESAGDAA DSAKDKSKSI 120
  121 TETIGDKISG AYDSVKEKAS DVADSFKAHS SDAQDTVEVS HHKYFNVFSS FE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.2
Match: 1xq8A
Description: Human micelle-bound alpha-synuclein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle