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View Structure Prediction Details

Protein: CE18525
Organism: Caenorhabditis elegans
Length: 384 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE18525.

Description E-value Query
Range
Subject
Range
gi|91084329 - gi|91084329|ref|XP_972528.1| PREDICTED: similar to Serine/threonine-protein phosphatase alpha-1 isof...
350.0 [0..56] [380..8481]

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Predicted Domain #1
Region A:
Residues: [1-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNSPNSSN PAATDAPKKT SVEPGSEANN WHITEADEKG FKLTDMIKKL LKPVFSKAIM  60
   61 FDEKEIHVLL TRVFKYYTSP PNKKTAPSAS ASATTSMSPP KPAANALLEL QAPINICGDT 120
  121 HGQYNDLLRI FNACGAATKT QYLFLGDYVD RGGHSLEVIM LLFSLKLAMP RKMHLLRGNH 180
  181 ELKAINKNYG FHAELKKRFQ REEVYESVYN HFNQVFSYMP LCAIVSKRIL CMHGGISPHL 240
  241 KSLDDIRAIP LPLETAKTHP LACDLLWADP EKDAKGFEPN KIRAISNVFG KKEVDDLCKR 300
  301 LDIDLIVRAH QVVEYGYAFF ADRRLITVFS ASRYQIELCN YAAVVVVNKM LELSFVQLKP 360
  361 EDFEVRRDEC EENAKDQTTS NVPH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.522879
Match: 1s70A
Description: Complex between protein ser/thr phosphatase-1 (delta) and the myosin phosphatase targeting subunit 1 (MYPT1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoric ester hydrolase activity 0.509050773280633 bayes_pls_golite062009
hydrolase activity 0.379703575045533 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.355334632309083 bayes_pls_golite062009
protein serine/threonine phosphatase activity 0.338021039820008 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.267819675108588 bayes_pls_golite062009
phosphatase activity 0.16038109142561 bayes_pls_golite062009
catalytic activity 0.058292778868172 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle