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View Structure Prediction Details

Protein: CE18521
Organism: Caenorhabditis elegans
Length: 703 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE18521.

Description E-value Query
Range
Subject
Range
gi|7022784, gi|1... - gi|7022784|dbj|BAA91722.1| unnamed protein product [Homo sapiens], gi|13177799|gb|AAH03666.1| NAD sy...
637.0 [0..5] [701..2]

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Predicted Domain #1
Region A:
Residues: [1-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQWDRRCRV ATCTVNNWAL DFKGNYERIV KTCEEAAALG ARIRLGPELE IPGYGCADHF  60
   61 FELDTERHSW EMLSKLVEKS KKWPNLLVVT GLPTRFRGLL YNCAAALRNG KLLFIRAKMG 120
  121 LADDNVYRES RWFVKWTETF KHYQMPLNSD IHFDQETVPF GDGILESSDN VRIGFEICEE 180
  181 LWSARSTNVR LAEQGVDIMC NGSGSHHILG KSNYRINQLI LGSSAKVGGV YLYANQRGCD 240
  241 GDRVYYDGAS SVAQNGDLLA QIHQFDIEDT SVVSAVVDLS DNQCFRHMKS SDRGNASDQV 300
  301 TVVPIRFDGK MTGGIKYNEK STAPIHNVED LQLSPIAELC HGPPAYLWTY LRRSGMAGYF 360
  361 IPLSGGQDSS AVAAMVRLMC EKVCGAIKRR RETDGGDDPA YYLGGKKVGE DPAELCNQVL 420
  421 FTCYMASEHS SDETRQCAEG LAKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.39794
Match: 1emsA
Description: NIT-FHIT fusion protein, C-terminal domain; NIT-FHIT fusion protein, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 2.8930848757764 bayes_pls_golite062009
catalytic activity 1.64442398754697 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.35962310800332 bayes_pls_golite062009
binding 1.19055167016953 bayes_pls_golite062009
nucleic acid binding 0.724655038971066 bayes_pls_golite062009
protein binding 0.399526580105167 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [445-703]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNSSHCGIFI DTIVTSILKV FNVAYGFMPS FQSPDNRETM ALQNIQARIR MVLSYLFAQL  60
   61 ALVSHKRPGG LLVLGTANVD ESLVGYLTKY DCSSADINPI GSVSKRDLRQ FLEIAYEKYG 120
  121 MAALRCVIDS TPTAELKPLV DGKVAQTDEA EIGLTYDELS VIGRLRKPGG MGPYGMFLKL 180
  181 LQLWGDKYSI DEIEEKVNKF FWRYRVNRHK ATVSTPAIHA ENYSPDDHRN DHRPFLYPDF 240
  241 SYQFERIREK VVELKKNST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.69897
Match: 1ee1A
Description: NH3-dependent NAD+-synthetase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle