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View Structure Prediction Details

Protein: ahcy-1
Organism: Caenorhabditis elegans
Length: 437 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ahcy-1.

Description E-value Query
Range
Subject
Range
gi|91083583 - gi|91083583|ref|XP_968366.1| PREDICTED: similar to adenosylhomocysteinase [Tribolium castaneum]
511.0 [0..4] [437..2]

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Predicted Domain #1
Region A:
Residues: [1-437]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQSKPAYKV ADIKLADFGR KEIILAENEM PGLMAMRSKY GPSQPLKGAR IAGCLHMTIQ  60
   61 TAVLIETLTA LGAEVQWSSC NIFSTQDHAA AAIAQTGVPV YAWKGETDEE YEWCIEQTIV 120
  121 FKDGQPLNMI LDDGGDLTNL VHAKYPQYLA GIRGLSEETT TGVHNLAKML AKGDLKVPAI 180
  181 NVNDSVTKSK FDNLYGIRES LPDGIKRATD VMLAGKVAVV AGYGDVGKGS AASLKAFGSR 240
  241 VIVTEIDPIN ALQAAMEGYE VTTLEEAAPK ANIIVTTTGC KDIVTGKHFE LLPNDAIVCN 300
  301 VGHFDCEIDV KWLNTNATKK DTIKPQVDRY TLKNGRHVIL LAEGRLVNLG CATGHPSFVM 360
  361 SNSFTNQVLA QVELWTKFGT PQEYKLGLYV LPKTLDEEVA YLHLAQLGVK LTKLSDEQAS 420
  421 YLGVPVAGPY KPDHYRY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 136.0
Match: 1li4A
Description: S-adenosylhomocystein hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
adenosylhomocysteinase activity 4.75102111339352 bayes_pls_golite062009
trialkylsulfonium hydrolase activity 4.75102111339352 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity 0.9367410227151 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.418775403210681 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.32207755075663 bayes_pls_golite062009
DNA binding 0.158019531459925 bayes_pls_golite062009
nucleic acid binding 0.0191997392158629 bayes_pls_golite062009
transcription regulator activity 0.012678711735872 bayes_pls_golite062009

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