YRC Public Data Repository - Protein Structure Prediction

Protein:	his-4
Organism:	Caenorhabditis elegans
Length:	141 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for his-4.

Description	E-value	Query Range	Subject Range
gi\|187036007, gi... - gi\|39595176\|emb\|CAE60213.1\| Hypothetical protein CBG03777 [Caenorhabditis briggsae], gi\|187036007\|em... gi\|157745709 - gi\|157745709\|ref\|XP_001667951.1\| Hypothetical protein CBG03777 [Caenorhabditis briggsae AF16]	212.0	[0..19]	[141..1]
gi\|76656039 - gi\|76656039\|ref\|XP_593475.2\| PREDICTED: similar to rCG23123 [Bos taurus]	195.0	[0..24]	[141..225]
gi\|50728600 - gi\|50728600\|ref\|XP_416197.1\| PREDICTED: similar to H2B histone family, member F [Gallus gallus]	194.0	[0..18]	[141..72]
his-54 - status:Predicted UniProt:Q27894 protein_id:AAK84513.1	190.0	[0..1]	[141..1]
gi\|109016350 - gi\|109016350\|ref\|XP_001104697.1\| PREDICTED: similar to Histone H2B 291B [Macaca mulatta]	189.0	[0..19]	[141..69]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAINPFFTLV QRPVQSIEMA PPKPSAKGAK KAAKTVTKPK DGKKRRHARK ESYSVYIYRV  60
   61 LKQVHPDTGV SSKAMSIMNS FVNDVFERIA AEASRLAHYN KRSTISSREI QTAVRLILPG 120
  121 ELAKHAVSEG TKAVTKYTSS K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.30103
Match:	1eqzB
Description:	Histone H2B
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.73700145395396	bayes_pls_golite062009
DNA binding	1.04127970884713	bayes_pls_golite062009
nucleic acid binding	0.86554830065808	bayes_pls_golite062009
transcription regulator activity	0.57702121108343	bayes_pls_golite062009
protein binding	0.260428734715028	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: