YRC Public Data Repository - Protein Structure Prediction

Protein:	clic-1
Organism:	Caenorhabditis elegans
Length:	226 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for clic-1.

Description	E-value	Query Range	Subject Range
gi\|225494, gi\|510 - gi\|510\|emb\|CAA28542.1\| unnamed protein product [Bos taurus], gi\|225494\|prf\|\|1304303B clathrin LCa	187.0	[0..18]	[224..5]
gi\|187023318, gi... - gi\|39581120\|emb\|CAE73198.1\| Hypothetical protein CBG20601 [Caenorhabditis briggsae], gi\|187023318\|em... gi\|157760699 - gi\|157760699\|ref\|XP_001672692.1\| Hypothetical protein CBG20601 [Caenorhabditis briggsae AF16]	186.0	[0..1]	[224..1]
gi\|73971344 - gi\|73971344\|ref\|XP_866787.1\| PREDICTED: similar to clathrin, light polypeptide A isoform a isoform 3...	186.0	[0..18]	[224..5]
gi\|30585415, gi\|... - gi\|60653991\|gb\|AAX29688.1\| clathrin light polypeptide [synthetic construct], gi\|30585415\|gb\|AAP36980...	183.0	[0..27]	[224..20]
gi\|71895347, gi\|... - gi\|71895347\|ref\|NP_001025780.1\| clathrin, light polypeptide [Gallus gallus], gi\|53130886\|emb\|CAG3177...	183.0	[0..16]	[223..1]
gi\|61362516, gi\|... - gi\|61362522\|gb\|AAX42237.1\| clathrin light polypeptide [synthetic construct], gi\|61362516\|gb\|AAX42236... gi\|158255592, gi... - gi\|4502899\|ref\|NP_001824.1\| clathrin, light polypeptide A isoform a [Homo sapiens], gi\|307118\|gb\|AAA...	182.0	[0..27]	[224..20]
CLCA_MOUSE - Clathrin light chain A OS=Mus musculus GN=Clta PE=1 SV=1	181.0	[0..16]	[224..7]

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Predicted Domain #1

Region A:
Residues: [1-113]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDPVADFLA REQNLFADFD GAPPAAAAAN PDAPEADAPA PALDDDFGDL QIAGDEPPPV  60
   61 VHPTDSGVDL DGLVDDNAAA PAIVVPAVEP MVNGNHSASS GGSKGPSPIL STV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.317	a.64.1	Saposin
View	Download	0.205	a.60.2	RuvA domain 2-like

Predicted Domain #2

Region A:
Residues: [114-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRIEAEKIRL WKAQQEQLLS KKDEAEEKKK IELRANAKKE LEEWYKQREK TLQLSHDENL  60
   61 KNEKSNQELF AKQQDGDAQW ETVNKLVDQQ KSKSGKDLSR LKTLLAGLKH AGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.0
Match:	1xi4J
Description:	Clathrin D6 Coat
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits