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View Structure Prediction Details

Protein: sepa-1
Organism: Caenorhabditis elegans
Length: 702 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sepa-1.

Description E-value Query
Range
Subject
Range
gi|25354063 - gi|25354063|pir||F87986 protein F44F1.6 [imported] - Caenorhabditis elegans
505.0 [0..7] [473..18]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPLSALTSN PAPSPPPKFA LGKCPATAIH VVSVLRPNRQ RFCYEKTDAG DLIPHKCLIC  60
   61 QPILTEKHIS PYYAVYSDLL EDFVLFGYNT MTGKMEQFIY AFK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDCFVEVNRP EIKYNPAFLV KGNVVVALNG PEGELVVIER DCRGLLSKES TSYGQFRTLP  60
   61 TAALRTLTLQ DLERDRWDRA ANSDEVKISS GNE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [197-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFDRLYAEYQ KNLPRFQVRQ CLHLNKEFLC VYSKTSGDYT RLEYIDETGD FQKISCTLCT  60
   61 CEVTESNLIP LYVERNASEL VIHVHNTENN QIEQYIYDVR TFGFVQVKRN LV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [309-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDPKKITSGL NLFMAENIDN RKVYMIMRGR DGRLQKETSG SGGFEKMQPV AVKTFQVQWV  60
   61 EMKTEFEKKK ASTERVEPQH P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [390-470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQTEGEDIME TVLAMVESFN CDLRKELGLT QDQEIPRKAP RVESAETEEN IVKNLEKLQI  60
   61 AKDPEEPTTA ASEGGNTYGY Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.522879
Match: 1r8uB
Description: NMR structure of CBP TAZ1/CITED2 complex
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [471-593]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELDDTMSEGL LEKEAESKHQ DANEPEPVKN VTYEPDVAAM DKKKKRRELK SRLNKINAQI  60
   61 DELEKRRMER AGKKQVVSSS VPSEEAAQVE APASPALAEN TNQISNEETP KIDIFEGYNG 120
  121 SFL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [594-702]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGTNTSKEWI VEDIRNHMVG KLLKAFWPRI QNVEEMNGEL FKKLIANARK CETEILEASN  60
   61 DRDEYYRLMQ LTVDQILKKT LKKDQRATEH NHQQPTQSSD ELAKNHEKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.522879
Match: 1sb0A
Description: Solution structure of the KIX domain of CBP bound to the transactivation domain of c-Myb
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle