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View Structure Prediction Details

Protein: sepa-1
Organism: Caenorhabditis elegans
Length: 702 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sepa-1.

Description E-value Query
Range
Subject
Range
gi|25354063 - gi|25354063|pir||F87986 protein F44F1.6 [imported] - Caenorhabditis elegans
505.0 [0..7] [473..18]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPLSALTSN PAPSPPPKFA LGKCPATAIH VVSVLRPNRQ RFCYEKTDAG DLIPHKCLIC  60
   61 QPILTEKHIS PYYAVYSDLL EDFVLFGYNT MTGKMEQFIY AFK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDCFVEVNRP EIKYNPAFLV KGNVVVALNG PEGELVVIER DCRGLLSKES TSYGQFRTLP  60
   61 TAALRTLTLQ DLERDRWDRA ANSDEVKISS GNE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [197-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFDRLYAEYQ KNLPRFQVRQ CLHLNKEFLC VYSKTSGDYT RLEYIDETGD FQKISCTLCT  60
   61 CEVTESNLIP LYVERNASEL VIHVHNTENN QIEQYIYDVR TFGFVQVKRN LV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [309-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDPKKITSGL NLFMAENIDN RKVYMIMRGR DGRLQKETSG SGGFEKMQPV AVKTFQVQWV  60
   61 EMKTEFEKKK ASTERVEPQH P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [390-470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQTEGEDIME TVLAMVESFN CDLRKELGLT QDQEIPRKAP RVESAETEEN IVKNLEKLQI  60
   61 AKDPEEPTTA ASEGGNTYGY Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.522879
Match: 1r8uB
Description: NMR structure of CBP TAZ1/CITED2 complex
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [471-593]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELDDTMSEGL LEKEAESKHQ DANEPEPVKN VTYEPDVAAM DKKKKRRELK SRLNKINAQI  60
   61 DELEKRRMER AGKKQVVSSS VPSEEAAQVE APASPALAEN TNQISNEETP KIDIFEGYNG 120
  121 SFL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [594-702]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGTNTSKEWI VEDIRNHMVG KLLKAFWPRI QNVEEMNGEL FKKLIANARK CETEILEASN  60
   61 DRDEYYRLMQ LTVDQILKKT LKKDQRATEH NHQQPTQSSD ELAKNHEKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.522879
Match: 1sb0A
Description: Solution structure of the KIX domain of CBP bound to the transactivation domain of c-Myb
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle