| Protein: | top-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 734 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for top-1.
| Description | E-value | Query Range |
Subject Range |
|
|
806.0 | [0..19] | [734..283] |
|
Region A: Residues: [1-171] |
1 11 21 31 41 51
| | | | | |
1 MSVVSNHHSN GNGNSTVYDT NGNDEIKKEV KDEPMASDSE VPFGELMKRD KKEKKQKKRK 60
61 AESGSDEDDY KPEKRKSSAK NGKKKDVGSD SEDDYKPEKK KSKKNNKKKA QESSEDDDEE 120
121 SEGDVSEEDV KPQKRKSKGA EKSKPSTSKK DAGGKKEPPK KKVKKEEDIE D
|
| Detection Method: |  |
| Confidence: | 1.32 |
| Match: | 2j63A |
| Description: | No description for 2j63A was found. |
|
Region A: Residues: [172-734] |
1 11 21 31 41 51
| | | | | |
1 IWEWWKEEKK PAGVKWNSLQ HCGPLFAPPY IPLPSHVHFK YGGEKMKLTL ETEEIAQFYA 60
61 GVLDHEYSTK EAFNKNFMKD WRKVMTVEER ERIHDLKKCD FRAIDAYQKE QREIRKAMTK 120
121 EEKLKIKEEK EAEVKIYGIA IIDGHRQKVA NFRIEPPGVF RGRGGHPKMG LIKKRIMPED 180
181 VIINCGKDTE IPKPPPGHKW KEVRHDNTVT WLCSWTESVL GQNKYIMLNP SSKIKGEKDF 240
241 EKYETARRLK KKIGGIRERY TDDFKSKEMR VRQRATALYF IDKLALRAGN EKDVDEAADT 300
301 VGCCSLRVEH IKLFDSAKLN EDDKKEKEFV VEFDFLGKDS IRYFNRVSVE KRVYKNLKIF 360
361 MEGKAPSDDL FDRLDTATLN DHLRSLMDGL TVKVFRTYNA SITLQEQLIK LTNPKDNVAA 420
421 KILSYNRANR QVAILCNHQR AVSKGFDESM QKLEQKIKDK KKEVKEAEAA LKSARGAEKE 480
481 KAQKKYDRLK EQLKKLKISR TDKDENKQIA LGTSKLNYID PRITVAWCKK FEVPLEKVFT 540
541 KTHREKFRWA IDMTNSSDEE YVF
|
| Detection Method: | |
| Confidence: | 1000.0 |
| Match: | 1nh3A |
| Description: | Eukaryotic DNA topoisomerase I, catalytic core; Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA topoisomerase activity | 8.60898665558163 | bayes_pls_golite062009 |
| DNA topoisomerase type I activity | 6.47633260167335 | bayes_pls_golite062009 |
| isomerase activity | 3.99087960186231 | bayes_pls_golite062009 |
| DNA binding | 2.6219583041012 | bayes_pls_golite062009 |
| nucleic acid binding | 2.52094994351474 | bayes_pls_golite062009 |
| binding | 2.48575835933363 | bayes_pls_golite062009 |
| double-stranded DNA binding | 2.2312769708203 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.791384719018446 | bayes_pls_golite062009 |
| chromatin binding | 0.64398646193812 | bayes_pls_golite062009 |
| catalytic activity | 0.609015643500883 | bayes_pls_golite062009 |
| protein binding | 0.497523852978755 | bayes_pls_golite062009 |
