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View Structure Prediction Details

Protein: CE10194
Organism: Caenorhabditis elegans
Length: 438 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE10194.

Description E-value Query
Range
Subject
Range
gi|9507011, gi|2... - gi|9507011|ref|NP_062013.1| protein tyrosine phosphatase, receptor type, S [Rattus norvegicus], gi|2...
401.0 [0..20] [437..1181]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKKKSKTKL LQKFADKFKK KKRSKSISMS KERGSELSRR PQKSRSNSKQ KATGPTSALP  60
   61 TDPKSKIDTT FMEITAKGFK SKKGKKLKKK KEETSASKSP STLTLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 2cs5A
Description: Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.66320966436771 bayes_pls_golite062009
binding 1.48311858793555 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [107-438]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAESHMDFSG NVKNVEKGVK VWIELLEKMD FRKTMEPEFK PIDTMKADLE KCQAFKKNID  60
   61 FSQSENVELY DTNRVKGGGE ADFFYHGSTL TIPSVTTKST ILAQLAIVDS PQSLESFWIM 120
  121 VASQKIQRLF ILLGEEELDK PTLSEYFPED FKEFKTIRVN NRKTVPKTEE QANTQLYYEV 180
  181 VPKDCAEAPF AMIEICDFWP DAKIPTMGYN RIAATAASVF ESDIDCDASC AIVSNYGAGR 240
  241 AGSFFVAVLA IEKLQAGEAP NIKEIALSVR SQRPAAIETL SQYMFTYVIA LTYGLKHVKD 300
  301 PALKIKTEKV ISQLEQFACE KMTEEDKDDT CE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.522879
Match: 2fh7A
Description: Crystal structure of the phosphatase domains of human PTP SIGMA
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle