YRC Public Data Repository - Protein Structure Prediction

Protein:	CE09663
Organism:	Caenorhabditis elegans
Length:	237 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE09663.

Description	E-value	Query Range	Subject Range
gi\|22124013, gi\|... - gi\|22124013\|ref\|NP_667436.1\| phosphopantothenoylcysteine synthase/decarboxylase [Yersinia pestis KIM... gi\|145212793, gi... - gi\|145601097\|ref\|YP_001165173.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopanto... gi\|165926067, gi... - gi\|165926067\|ref\|ZP_02221899.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|166213762, gi... - gi\|166213762\|ref\|ZP_02239797.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|166011425, gi... - gi\|166011425\|ref\|ZP_02232323.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|167418905, gi... - gi\|167418905\|ref\|ZP_02310658.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|167402115, gi... - gi\|167402115\|ref\|ZP_02307592.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|186893391, gi... - gi\|186893391\|ref\|YP_001870503.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyst... gi\|89103898 - gi\|89103898\|ref\|ZP_01176458.1\| COG0452: Phosphopantothenoylcysteine synthetase/decarboxylase [Yersin... gi\|167426675, gi... - gi\|167426675\|ref\|ZP_02318428.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|108809485, gi... - gi\|108809485\|ref\|YP_653401.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothe... gi\|77634073, gi\|... - gi\|77634073\|ref\|ZP_00796182.1\| COG0452: Phosphopantothenoylcysteine synthetase/decarboxylase [Yersin... gi\|108813962, gi... - gi\|108813962\|ref\|YP_649729.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothe...	229.0	[0..23]	[237..26]
gi\|22777187, gi\|... - gi\|23098959\|ref\|NP_692425.1\| pantothenate metabolism [Oceanobacillus iheyensis HTE831], gi\|22777187\|...	229.0	[0..39]	[237..1]
gi\|56419704, gi\|... - gi\|56419704\|ref\|YP_147022.1\| pantothenate metabolism flavoprotein [Geobacillus kaustophilus HTA426],...	228.0	[0..39]	[237..1]
gi\|114307810, gi... - gi\|71550056\|ref\|ZP_00670204.1\| DNA/pantothenate metabolism flavoprotein [Nitrosomonas eutropha C71],...	227.0	[0..39]	[237..6]
gi\|113527778, gi... - gi\|113869002\|ref\|YP_727491.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothe...	226.0	[0..38]	[237..1]
gi\|30138797, gi\|... - gi\|30249434\|ref\|NP_841504.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothen...	225.0	[0..34]	[237..1]
gi\|109483552 - gi\|109483552\|ref\|XP_343398.2\| PREDICTED: similar to phosphopantothenoylcysteine decarboxylase [Rattu...	224.0	[0..16]	[235..91]
gi\|77630874 - gi\|77630874\|ref\|ZP_00793460.1\| COG0452: Phosphopantothenoylcysteine synthetase/decarboxylase [Yersin...	223.0	[0..36]	[237..1]
gi\|15978163, gi\|... - gi\|16120401\|ref\|NP_403714.1\| phosphopantothenoylcysteine synthase/decarboxylase [Yersinia pestis CO9... gi\|150260888, gi... - gi\|150260888\|ref\|ZP_01917616.1\| DNA/pantothenate metabolism flavoprotein [Yersinia pestis CA88-4125]... gi\|51594403, gi\|... - gi\|51594403\|ref\|YP_068594.1\| phosphopantothenoylcysteine synthase/decarboxylase [Yersinia pseudotube... Q66GD7\|Q66GD7_YERPS - DNA/pantothenate metabolism flavoprotein - Yersinia pseudotuberculosis gi\|165936230, gi... - gi\|165936230\|ref\|ZP_02224799.1\| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cyste... gi\|45434769, gi\|... - gi\|45439914\|ref\|NP_991453.1\| phosphopantothenoylcysteine synthase/decarboxylase [Yersinia pestis bio... gi\|25322282 - pir\|\|AI0006 DNA/pantothenate metabolism flavoprotein [imported] - Yersinia pestis (strain CO92)	223.0	[0..36]	[237..1]
gi\|15894997, gi\|... - gi\|15894997\|ref\|NP_348346.1\| bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothen... gi\|25322279 - pir\|\|C97112 flavoprotein involved in panthothenate metabolism, YLOI B. subtilis ortholog [imported] ...	223.0	[0..43]	[237..4]

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Predicted Domain #1

Region A:
Residues: [1-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDELSVKRH KSDPDESIEE IMPEIRPPLT RTHKIVRDES GKHNLLLILT GSIAVMKAPE  60
   61 LISELYEKIG RDRILIKVVT TENAMKLCHI QKLEFDEIVY EDRDEWSMWR ERGDKVLHIE 120
  121 LRKWADSALI APLDANTMAK IANGLCDNLV TSIIRAWDLS KPCYFAPAMN THMWENPLTM 180
  181 QHRTVLKSQL KFKEICPIQK ELICGDVGTG AMASIGTIVS LVAALVRDQQ AVRIQCG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.39794
Match:	1qzuA
Description:	crystal structure of human phosphopantothenoylcysteine decarboxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphopantothenoylcysteine decarboxylase activity	3.86093811191169	bayes_pls_golite062009
phosphopantothenate--cysteine ligase activity	2.64345867885176	bayes_pls_golite062009
carboxy-lyase activity	1.79168084682693	bayes_pls_golite062009
catalytic activity	1.51672397362026	bayes_pls_golite062009
carbon-carbon lyase activity	1.03827559540394	bayes_pls_golite062009
binding	0.69350040563585	bayes_pls_golite062009
protein binding	0.003958060867923	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: