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View Structure Prediction Details

Protein: ftn-1
Organism: Caenorhabditis elegans
Length: 170 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ftn-1.

Description E-value Query
Range
Subject
Range
gi|47125326 - gi|47125326|gb|AAH70494.1| FTH1 protein [Homo sapiens]
259.0 [0..2] [170..56]
gi|114637918 - gi|114637918|ref|XP_001140124.1| PREDICTED: similar to Ferritin heavy chain (Ferritin H subunit) (Pr...
257.0 [0..2] [170..114]
gi|83404987 - gi|83404987|gb|AAI11079.1| Fth1 protein [Rattus norvegicus]
253.0 [0..2] [169..57]
gi|28630234 - gi|28630234|gb|AAN63032.1| ferritin heavy chain polypeptide 1 [Branchiostoma lanceolatum]
241.0 [0..1] [170..2]
gi|46562303 - gi|46562303|gb|AAT01287.1| ferritin [Coturnix japonica]
241.0 [0..2] [170..6]
FRIH_CHICK - Ferritin heavy chain OS=Gallus gallus GN=FTH PE=2 SV=2
240.0 [0..2] [170..6]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLARQNYHD EVEAAVNKQI NVELYASYVY LSMSAHFDRD DIALRNIAKF FKEQSDEERG  60
   61 HATELMRIQA VRGGRVAMQN IQKPEKDEWG TVLEAFEAAL ALERANNASL LKLHGIAEQR 120
  121 NDAHLTNYIQ EKYLEEQVHS INEFARHIAN IKRAGPGLGE YLFDKEEFSD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.69897
Match: 1fhaA
Description: SOLVING THE STRUCTURE OF HUMAN H FERRITIN BY GENETICALLY ENGINEERING INTERMOLECULAR CRYSTAL CONTACTS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ferric iron binding 5.55100638826026 bayes_pls_golite062009
iron ion binding 3.10225782829614 bayes_pls_golite062009
binding 1.95813969002966 bayes_pls_golite062009
transition metal ion binding 1.70242943635222 bayes_pls_golite062009
cation binding 1.66873432300081 bayes_pls_golite062009
metal ion binding 1.66873432300081 bayes_pls_golite062009
ion binding 1.66140448750278 bayes_pls_golite062009
ribonucleoside-diphosphate reductase activity 0.366005079572569 bayes_pls_golite062009
protein binding 0.30514049100341 bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor 0.289628933165632 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle