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View Structure Prediction Details

Protein: CE08876
Organism: Caenorhabditis elegans
Length: 713 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE08876.

Description E-value Query
Range
Subject
Range
gi|39593005, gi|... - gi|39593005|emb|CAE62619.1| Hypothetical protein CBG06741 [Caenorhabditis briggsae], gi|187034279|em...
520.0 [0..34] [713..1]

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Predicted Domain #1
Region A:
Residues: [1-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKHLFLFLF IKSSIAYNFY WYDKTQTLQN RQTMVHLFEW KWADVAKECE NFLQYYGYGA  60
   61 VQVSPPMEHL KAFPNNNYPW WVRYQPVSYK LDSRSGNEQE FQDMVNRCNK VGVRIIVDIV 120
  121 MNHMVGIGQK SGNGVGSSGS SSFDGTHGVQ SFPGVPYSLG DFNNPKCDGD IQGSDYQNSA 180
  181 EHVKDCRLVG LLDLNQASAT VRAKIVAYLN KLVDMGVAGF RHDASKHMWP QDILNILNDV 240
  241 KDLRSDIYGS NQRPFAVHEV IDRGGEAVKC GDYFGNGRYT NFNFGAAVSA AAKQQSDWKY 300
  301 LANLGPGYGY GNNEDHDVLN FIDNHDNQRD SSPYVVTYKD GQKYNLAVGF MLAWPYGYPR 360
  361 VMSSFAFSYS DQSPPNSGAS NDYATTSPTF NGDQTCNSNS GWVCEHRWPA IRQMAKFRSA 420
  421 VQGTAAADIV TDTRRIAFAR DGKGFFALNQ QDGAWTKIFA TNLPAGDYCD HFSGGLDNGK 480
  481 CVGTKITVRD DHTSYLSVPS NSIVAISLDS KLTPYTPPAP PSGYSTTVIL LKKDTNPGQN 540
  541 IFVRGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.0
Match: 1bsiA
Description: HUMAN PANCREATIC ALPHA-AMYLASE FROM PICHIA PASTORIS, GLYCOSYLATED PROTEIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, hydrolyzing O-glycosyl compounds 4.11319792356479 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.92012282533754 bayes_pls_golite062009
hydrolase activity 2.30046070709431 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
chitinase activity 1.8132391603727 bayes_pls_golite062009
amylase activity 1.38959979746158 bayes_pls_golite062009
glucosidase activity 0.528679164808812 bayes_pls_golite062009
hexosaminidase activity 0.423006654245821 bayes_pls_golite062009
receptor binding 0.131188274937943 bayes_pls_golite062009
alpha-galactosidase activity 0.113591899485521 bayes_pls_golite062009
carbohydrate binding 0.102788238231918 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [547-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSQAHNGKCS TGPYQQSSDP CAIPMYHATT VPFVFAEYLT WSQQDNYLDF EGAEINQGTH  60
   61 D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [608-713]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAAAFGTPLA YSTNDKTAIE YQPYNKYGPG YWIAVLRMDC SKAEQGWFEV KGYETPDIGW  60
   61 EGDIKQGSCS GSVGGSAPFS SINHVAKCGA VNVFTWGSAS CVIDSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 1ac0A
Description: GLUCOAMYLASE, GRANULAR STARCH-BINDING DOMAIN COMPLEX WITH CYCLODEXTRIN, NMR, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle