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View Structure Prediction Details

Protein: CE08627
Organism: Caenorhabditis elegans
Length: 444 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE08627.

Description E-value Query
Range
Subject
Range
CE32824 - status:Confirmed UniProt:Q8I7H5 protein_id:AAN84844.1
238.0 [0..95] [444..10]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQKTDFLSK IFSSSSHPLT GSQNIVVKDP QTLDFAMQSQ NEIVCSLRER SHMNTMSYAQ  60
   61 TQMMAIDEIR AFQSEGHLHL KYISLIIAMM AETAV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTSRSWFPYF SCPSKSQRLA EAEGRILSAL GIKYLARLIQ IPFKNTEIST ITVNCESEQP  60
   61 IVKAKYPIVL IHGFGAGVAL WGSAIKRLAQ FQTVHAFDLP GFGRSSRPKF SSDPETAETE 120
  121 MIDSIEQWRD KMNLEKMNLV GHSFGGYLAT SYALKYPKRV ENLILADPWG FNEMDPEFAQ 180
  181 KLTSRQKNIF WVIQQFNPLA VLRLVGGYGP SLVRRLRPDL ALKYSEDVYD YIYLANSRDP 240
  241 TGEEVFKCLS ENLGWAKQPM SKRFHELDNT VPVTFIHGER SWIDWRTTRR LFGELEHVES 300
  301 HIMDSAGHHV YADDADKFVQ LVIGSLKDGK TGELVPEEVN LEEEIVTPI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 1s8oA
Description: Human soluble Epoxide Hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.39629727416851 bayes_pls_golite062009
lipase activity 0.849473630399459 bayes_pls_golite062009
binding 0.780364496307855 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.560001331598537 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009
hydrolase activity 0.175922778894906 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle