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View Structure Prediction Details

Protein: dsc-1
Organism: Caenorhabditis elegans
Length: 310 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dsc-1.

Description E-value Query
Range
Subject
Range
gi|4322076 - gi|4322076|gb|AAD15947.1| homeobox protein [Danio rerio]
147.0 [0..7] [248..1]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPHTNLNNV FDFPDLPMLL PKSEALSVTT DFSVPPVQQG AQQFHPPRNL GPQLARRWSC  60
   61 GDSQHADEPP ASYYHNLGVA LHNHFQMSNQ HYLSDFDCPT TVSPISSAHE TGQLPQLSPY 120
  121 DHIGNQDPHM FSPHAYGNSM IPDNSYFENA SRSISAPN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [159-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGNSTLNPSL MSSDNAQSCG GRRRFRTNFT ELQSTFLEDS FKESHYPDHK AKKYMADFLK  60
   61 IPEDRITVWF QNRRAKWRRK EHRQRDRTRN ESFSGGSNSF DFACFSAQHP DDGPNAKHPN 120
  121 SFGIPNQPMS LDQFPMNTEQ DFPEFPSLQE HQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1fjlA
Description: Paired protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.20352928045795 bayes_pls_golite062009
transcription regulator activity 0.835457558255133 bayes_pls_golite062009
DNA binding 0.655670804261679 bayes_pls_golite062009
nucleic acid binding 0.439599063396733 bayes_pls_golite062009
transcription factor activity 0.345340917029646 bayes_pls_golite062009
protein binding 0.0926151783365978 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle