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View Structure Prediction Details

Protein: clec-41
Organism: Caenorhabditis elegans
Length: 545 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for clec-41.

Description E-value Query
Range
Subject
Range
gi|157763608 - gi|157763608|ref|XP_001674146.1| Hypothetical protein CBG09432 [Caenorhabditis briggsae AF16]
gi|187031855, gi... - gi|39593191|emb|CAE64660.1| Hypothetical protein CBG09432 [Caenorhabditis briggsae], gi|187031855|em...
231.0 [0..14] [544..15]

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Predicted Domain #1
Region A:
Residues: [1-150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWFHSTLLLA ILVAVSADTC PAGFTALSTS KKCVKLITDV AKHSDATANC SSYGGHLISV  60
   61 QNAIDNNAYL QLAAVSVTPY WLGIKCSLSG NPASCQWDDQ SGNAGGYNGF APGYPLVEVG 120
  121 NCVYVPTSGS FAGKWLSGDC NTMSLNFICE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 1sl6A
Description: Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13629480035749 bayes_pls_golite062009
carbohydrate binding 0.44675717945952 bayes_pls_golite062009
protein binding 0.059857076934361 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [151-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAPTSPITDT CSFQYNGNCY YPSLSALPKQ DAQFSCQQAC GNLVSIHSIE ENNYVQSLFT  60
   61 TNAPTYIRIG AVANNQNSNS WIDGTSWNYD NIGYSNINLG MCWSMALSND IVSTGKWISS 120
  121 YCDTSLPFVC KRKVGTQCGT TSGPTQTPGQ CTSPMFMDNS GRFYSPSWPY SYI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.09691
Match: 1g1qA
Description: E-selectin; E-selectin, EGF-domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13629480035749 bayes_pls_golite062009
carbohydrate binding 0.44675717945952 bayes_pls_golite062009
protein binding 0.059857076934361 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [324-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEQNPCNYIL DTPVGSLVQI RFPVMNLDSQ ASISIYSRIE DTTPLVVLQG NSASNQWYTS  60
   61 TTNTMKVVFR PCIANCPNDG VNYRWEADFK PSTDVTQPPV TVTPNPNNPS GCNSTILVAP 120
  121 GSISTPNYPN YYPNFLLCMY HLSTTGGYRI NLDFGAIDTE QCCDIIEVHD GPLLGSPKLG 180
  181 IVSGTWPAHA KTYQSSSNSM LVTFSTDSSG QGSGFSANFW AL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.69897
Match: 1nt0A
Description: Mannose-binding protein associated serine protease 2, MASP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 1.40618339011373 bayes_pls_golite062009
growth factor activity 0.25853515067422 bayes_pls_golite062009
binding 0.246892638113776 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle