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View Structure Prediction Details

Protein: tgt-1
Organism: Caenorhabditis elegans
Length: 400 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tgt-1.

Description E-value Query
Range
Subject
Range
TGT_CALS4 - Queuine tRNA-ribosyltransferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15...
TGT_THETN - Queuine tRNA-ribosyltransferase OS=Thermoanaerobacter tengcongensis GN=tgt PE=3 SV=1
563.0 [0..1] [369..4]

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Predicted Domain #1
Region A:
Residues: [1-400]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYDVLARAG FARRGNLHLP HSIVETPVFM PVGTQGTMKG IVPEQLVSMD CRILLCNTYH  60
   61 LGHRPGHERV KAAGGLHKMM NWNRSILTDS GGFQMVSLSK LMTVDENGVN FESPHTGEMM 120
  121 ALPPEKSIEI QQALGADIMM QLDHVIHVLT TGDIVKEAMH RSIRWLDRCK VAHTRDDQAM 180
  181 FPILQGGLNL ELRKECAKEM AKRAKVGIAI GGLSGGEEKD HFWRVVAACC AALPPHLPRY 240
  241 VMGVGFPVDL VICSFLGADM FDCVYPTRTA RFGTAMVRRG GLMQLNQKRY KEDFLPIDKK 300
  301 CECNTCKNYT RAYIHSIVGK ETVGCHLVSV HNIKHQLDLM RDVRQAIQSN SVEQFLKQFL 360
  361 YDYYGPIQSE NPSKQDSEKM REVPQWVRDA VDHMGYKLDF 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 144.0
Match: 1ozmA
Description: Y106F mutant of Z. mobilis TGT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
queuine tRNA-ribosyltransferase activity 5.68673071384353 bayes_pls_golite062009
transferase activity 3.21194535271238 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 2.84864811414771 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.53039738178366 bayes_pls_golite062009
catalytic activity 2.02168745464921 bayes_pls_golite062009
binding 1.29132603807317 bayes_pls_golite062009
protein binding 0.136438951368546 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle