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View Structure Prediction Details

Protein: CE06282
Organism: Caenorhabditis elegans
Length: 432 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE06282.

Description E-value Query
Range
Subject
Range
CHIA_RAT - Acidic mammalian chitinase OS=Rattus norvegicus GN=Chia PE=2 SV=1
330.0 [0..34] [430..1]

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Predicted Domain #1
Region A:
Residues: [1-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNIKSEQKE SEELVLPNDR PQYEQRVTKQ PTSGKYIIIT ITLISIIIVG FGLGLCAQIY  60
   61 FQAESDVLPI CDKRIIGYYS GSGTSNITST QLSNLTHTVF AFVYMTPDGT LLFNNQIEKN 120
  121 RFLKLKEVVR NGNSKIKLMF SIGGKDNSKY FSSVIPSEER IQTFIESILE FLEAYDLDGV 180
  181 DLFWKWPEEE YRDAYFAFIN QLRKTFEAKK KYYILSIVIP PPTLDGWGKK RLNKIIESVD 240
  241 FINAYSTDYY TPLADNLSDD IAGPSAPIYF GAQGKSERNV HHTARNYSCL TKQASKFNIV 300
  301 IPFYATLWEN VYETVLDSKR GVYRHVAPFY GRTVGKTYLS RLAVKQEGFQ VESYSYDPAP 360
  361 RAAFSYNRTI GIYLTFETKE SIRAKIDYVK DRILGGVWIF SVDMDDETNS QLKAVSFDGF 420
  421 CTIGNGSKYE CV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.30103
Match: 1wawA
Description: Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against human chitinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
imaginal disc growth factor activity 3.9608908661313 bayes_pls_golite062009
growth factor activity 2.18932950777991 bayes_pls_golite062009
chitinase activity 1.96922204880842 bayes_pls_golite062009
receptor binding 1.89435893935497 bayes_pls_golite062009
binding 1.1885466730171 bayes_pls_golite062009
carbohydrate binding 0.80333288291596 bayes_pls_golite062009
protein binding 0.690517649847952 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 0.141107738097631 bayes_pls_golite062009
pattern binding 0.113396113487931 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle