YRC Public Data Repository - Protein Structure Prediction

Protein:	aly-3
Organism:	Caenorhabditis elegans
Length:	240 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aly-3.

Description	E-value	Query Range	Subject Range
gi\|76633747 - gi\|76633747\|ref\|XP_881817.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	164.0	[0..14]	[227..217]
gi\|1082703, gi\|6... - gi\|693937\|emb\|CAA88401.1\| polyadenylate binding protein II [Homo sapiens], pir\|\|S52491 polyadenylate...	160.0	[0..15]	[231..193]
gi\|73976787 - gi\|73976787\|ref\|XP_857499.1\| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...	159.0	[0..15]	[231..218]
gi\|109120206 - gi\|109120206\|ref\|XP_001090892.1\| PREDICTED: poly(A) binding protein, cytoplasmic 1 isoform 1 [Macaca...	157.0	[0..15]	[231..218]

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Predicted Domain #1

Region A:
Residues: [1-155]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKATNVDLS LEDIISKTRK TTGSIQKKSF GGARRGNTRP TGLPRRSGGS GGWKDLDAVQ  60
   61 NHGISSRGND SKVIRVNISN LAPTVISSDL EELFGDYRLS SVSVNFNEHG DSLGTGDISL 120
  121 TKRDAERLVQ KFSGVALDGK IMKFAVIDSS NMAGR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.39794
Match:	1po6A
Description:	Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.950788308762215	bayes_pls_golite062009
nucleic acid binding	0.29562225149076	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [156-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDFGNRSRSS PGRSSRGFQS GPRRNNGKPE DFLRDGVHAG DIKRGGAGRG GFRKGGRGGA  60
   61 RDAKPKKTEA ELDAELEAYM AKRNA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: