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View Structure Prediction Details

Protein: vps-45
Organism: Caenorhabditis elegans
Length: 547 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vps-45.

Description E-value Query
Range
Subject
Range
VPS45_RAT - Vacuolar protein sorting-associated protein 45 OS=Rattus norvegicus GN=Vps45 PE=1 SV=1
482.0 [0..1] [537..1]

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Predicted Domain #1
Region A:
Residues: [1-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLVQSSRKL IQDMIQLAGS QMKLLLMDGE TTPTVSCAFA QSEVMQKEVY IFDRIENKTS  60
   61 SENIKNLKCV VFVRPTPKNI ERLVKELQEP RFSQYYLYFT NTINKYDVKR LAEADKNETV 120
  121 REVQEVFLDG VPIRKDLFTL NLTHIFDSSF TLKEEAAERI KCGIIALLLQ LKKAPAVRYQ 180
  181 KSSPSCKKVA DDVAQFIRRE NGLFENSRAD TTLLIIERSQ DAVTPLLNQW TYEAMIHEML 240
  241 TLTNNRCTCT DQNIVLSELH DEFFARNITA NFGEIGQNIK TLISEFQEKK HINKNLESIQ 300
  301 DMKKFVEDYP QFKKISGTVS KHVSLVGELS NLVQKHNLLG VSEVEQAIVS DGDHGKCINL 360
  361 VRGLLKNTKT REVDIIRLVL LYALRFENAP GNELNSLISQ LRPQHPKIHQ TVSTLLKYGG 420
  421 LSRRPADLFG GESTIDITKR FIKGLKGVEN IYTQHSPYLK NMIESCQRGR LDNYPLLSNE 480
  481 CDRMDNIIVF IVGGATYEEA AYVRSLNEKR MQGYGGPAVV LAGSSMLNTK SFLEEFANVD 540
  541 KNTGAVH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.0
Match: 1epuA
Description: Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
SNARE binding 4.56428593085019 bayes_pls_golite062009
syntaxin binding 3.46044132736061 bayes_pls_golite062009
binding 2.7837022903231 bayes_pls_golite062009
protein binding 2.77285532000616 bayes_pls_golite062009
syntaxin-1 binding 0.269372794919901 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle