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View Structure Prediction Details

Protein: CE03271
Organism: Caenorhabditis elegans
Length: 428 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE03271.

Description E-value Query
Range
Subject
Range
gi|21426807, gi|... - gi|21426807|ref|NP_653344.1| carboxylesterase 6 [Rattus norvegicus], gi|21307643|gb|AAK61610.1| carb...
275.0 [0..2] [420..1]

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Predicted Domain #1
Region A:
Residues: [1-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKAKKESNY TKGIVPVLIT IFLLITGYAL YKPLPEGFTI SKWDRAVMHV VEPALRVAYY  60
   61 YPSRMFTKPS NMVQWTRGAL NTLSKTLGLL VNTHGQVDIK WHKWNETPVK VYRPTNNKTS 120
  121 TDGAVLFIHG GGFALGNVDM YDSLVKRMAY EMKTLFISIE YRLSPETVFP GGILDCEAAI 180
  181 DHFFDFGAVQ FGVNTSKVVI MGDSAGGNLA TVIAQRRAAR NSFPKLAGQV LIYPLLQMAD 240
  241 MQTVSYRYFH SRLRGYALVD PESVAYYYMF YAGIDMDEKA YLVPSVISNG HVANHLQSEA 300
  301 SEIMSYKSVI EMKHNYKNHS ITERWEVSQS YEAQDLMEPF LTNPDFSPLM RKDLSNLPPT 360
  361 MVITCEFDIL RDEGLIYGER LKVSGVPTTT IHYENGFHAM LNFHSELDEA SKSVDDIEQW 420
  421 TLNAINNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.30103
Match: 1mx1A
Description: Mammalian carboxylesterase (liver carboxylesterase I)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 1.95306186248921 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
lipase activity 0.849473630399459 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.282381128231187 bayes_pls_golite062009
binding 0.112743564301567 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle