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View Structure Prediction Details

Protein: CE02518
Organism: Caenorhabditis elegans
Length: 706 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE02518.

Description E-value Query
Range
Subject
Range
gi|92110524, gi|... - gi|92110524|gb|ABE73346.1| putative calcium-dependent protein kinase 2 [Isatis tinctoria], gi|921105...
345.0 [0..35] [654..30]

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Predicted Domain #1
Region A:
Residues: [1-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVIAYVDANL QTNRQTIYFD HDLNRNKYNT IQLKKLTMTQ DSDSEYEIER IIDHVSFLEA  60
   61 YESFYGQNVK RFAAIFSEER FKRTKKPQLI SNYFFLVKWL GYGNKEMTWE PESNIPDSVY 120
  121 LYEYKKLNNM VMNRMNLKVS LTFTSRRKGY TPPVILEELQ ERKPKPQFLN MSNMAITLND 180
  181 NLNNGKFGIV PVPKYKKKFG QNVNYLKFGN EVYKMKNVSF KDSTNNDIDN RVQQHHHEDR 240
  241 SFLQSMIKHN NIVRMRDLFV SYNKLDETVN ITSIYDWCHQ NLRQQLNNEK VSWKKVCRDI 300
  301 LNALSFIHPY GIHQGVSLDH IYYHKGGTYK LSHFNNFFFG KRIPAEKVKS DRVELAPRLY 360
  361 NLKFKLGRNS DIYALAIVLL QCHNKKFSFR VNPSSVMEIE EDIAKGMSAF ENKDDRHFLK 420
  421 SLLRARLHVY HGSGHYRFTS SSLLHHPVLQ EPTARSVECF YFHSMLASPM KEIIHYHAND 480
  481 KISDVLQRFI SLYHTSQEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.0
Match: 1omwA
Description: G-protein coupled receptor kinase 2, N-terminal domain; G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1); G-protein coupled receptor kinase 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase activity 1.3154140242701 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.22869951697712 bayes_pls_golite062009
kinase activity 1.12837603902755 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.00935990325065 bayes_pls_golite062009
binding 0.924367187251007 bayes_pls_golite062009
protein serine/threonine kinase activity 0.756667895757179 bayes_pls_golite062009
protein binding 0.487852814552584 bayes_pls_golite062009
transferase activity 0.0327975721084419 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [500-706]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDKKYIMMFT KDTSSCDSVV LLNSLENFER VVDIDLTIMK NTLLIAPIIL PSPENENCQK  60
   61 FLIIYEQELG GCPIVIETPE VNAAKFAKQL KEYSVSHEYR NRRLGLFPKL PGGDQQENGG 120
  121 LPEFSHHVWQ MQLESNDDTV IKNRFDIASE IEMPLSGEML EWDDVAGIAN YGEILRNNSD 180
  181 NTTSRRKRET CSSDELDEAH AKREKVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.09691
Match: 2aaoA
Description: Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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