| Protein: | pme-2 |
| Organism: | Caenorhabditis elegans |
| Length: | 538 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
|
Region A: Residues: [1-145] |
1 11 21 31 41 51
| | | | | |
1 MSIINDENGR GYKVHLCKTN IAQNNNKFYD MELLDEGGDF IVKLINGRIG YRGVTQLKDF 60
61 DDLDRAKKFF ESKFYEKTHL HWEERDDEPV PNKYAVVELA TNARQTEKEV KKEEPEPEPK 120
121 VDEKNTRGRK KRGIVKEKKE IKKEE
|
| Detection Method: |  |
| Confidence: | 24.221849 |
| Match: | 2cr9A |
| Description: | Solution structure of WGR domain of poly(ADP-ribose) polymerase-1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [146-538] |
1 11 21 31 41 51
| | | | | |
1 EPVEEVNEKL KELMKCICDE DVHLGLLKQL KFNEAFGRPI DCLSLAQLTT GYEILSKIEE 60
61 SIGGKSARRS TRGRPRVADR VLAVKSDGPS LHDINKYYSL IPHSFGFCVP PKIDSHAKIQ 120
121 AERELLDALK GSIEASLELK DLKKTASSKD IYQRLYERLP CHLEPVSEEI AGKIGDCLAM 180
181 RGPTHCYKLS LIDAFELKDP NEIPTEAPVE VQEVPKKRGR KSTKTAAPTV PPPTTKRLLW 240
241 HGTRVTNVFS ILMNGLQFPV GDRCGLMFGN GVYFANVPTK SANYCCPEAS KRVFMLLCEV 300
301 ETANPLVLYE SEIDADEKME KAKKTSVYAA GKHTPRDTVE INGIPAFKSN LETIEEETRL 360
361 LYDEYVMFNK EHFKIKYVVE VKVDRLTAKE MMA
|
| Detection Method: | |
| Confidence: | 93.30103 |
| Match: | 1uk0A |
| Description: | Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| NAD+ ADP-ribosyltransferase activity | 7.15093533922724 | bayes_pls_golite062009 |
| NAD(P)+-protein-arginine ADP-ribosyltransferase activity | 2.57756389034544 | bayes_pls_golite062009 |
| binding | 1.5526011325617 | bayes_pls_golite062009 |
| transferase activity | 1.5222353301058 | bayes_pls_golite062009 |
| nucleic acid binding | 0.901890891144085 | bayes_pls_golite062009 |
| catalytic activity | 0.886617552734979 | bayes_pls_golite062009 |
| DNA binding | 0.850361767185031 | bayes_pls_golite062009 |
| protein binding | 0.610837485187136 | bayes_pls_golite062009 |
| NAD+ nucleosidase activity | 0.309947239058532 | bayes_pls_golite062009 |
| transferase activity, transferring pentosyl groups | 0.29605207876765 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.209002662548996 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.147630885386744 | bayes_pls_golite062009 |
| transferase activity, transferring glycosyl groups | 0.0346323577656257 | bayes_pls_golite062009 |
