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View Structure Prediction Details

Protein: CE01108
Organism: Caenorhabditis elegans
Length: 784 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE01108.

Description E-value Query
Range
Subject
Range
gi|89949322, gi|... - gi|90019722|ref|YP_525549.1| DNA polymerase I [Saccharophagus degradans 2-40], gi|89949322|gb|ABD793...
459.0 [0..133] [778..40]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDTTSSEDV PENKQKSLKF EIIDARMKIF KDIVKSKSSE SVKEEQIYQK SLEFFDEDLK  60
   61 SSEESVSNEE IKTGSEKELE PLNVFDIILI MLQQLPERKK PIGSLLSKWI LMNFMNWMQD 120
  121 KQSIMEQQM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [130-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEYYQKKAGL ACVKEPKNEE YLLQIFKISK EFVIDLRKSK VQEYLENQKF KEAAEIVMKH  60
   61 EVVDDYSFEQ ITLPLILCDK VQIVDELLKI SKKLQKSYIS FLDQFVAETD ETVNAFFEPY 120
  121 KEKGMVTINL SRFHGKSLTI FMQKFFNGQV KQFKFDLEER RDAPKFVANM KRKALKYFVG 180
  181 KRFEDHEMND ELFCEHMKST LPECTDKTIV QFLILLWDTC IYERRIEALF WATYSNIDRN 240
  241 SKYMPPDLKE ELENPTTEMK NGLEKLQALR TTKNCQEEDE QLYVF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 1taqA
Description: STRUCTURE OF TAQ DNA POLYMERASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.845290320008287 bayes_pls_golite062009
hydrolase activity 0.31554871338907 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.12799711467808 bayes_pls_golite062009
nuclease activity 0.0878151841480506 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [415-784]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEQKKYPIRI VQNEQDLEIL LSELGELEEG MYIGYDSEFK PYHLIDVSTS RLAIIQLFFK  60
   61 DKAWLINCVA IDNLASRDDV WIRLYKGLFE SNKFSIVGFD IRQDIEAMFT VPSINKNFKI 120
  121 ENIQNVICVK SLAENVNALS MDILNLSTKT SKLSVLADHL VGLKMDKSEQ CGNWQCRPLR 180
  181 RNQIIYAVMD AVAVFEVFQK IVEVVRKHEL DAEKLLVESH MITVKKEKVR RDCKNISLIP 240
  241 WNEFYQIIHT HRNPEKPLQK PSELKIVVDT MVLGLGKNLR LLGFDVYIPR DVTELKEFLR 300
  301 KMDKMEESEQ RLVISVPSRS YEMLKSDNPN AKFVLIPNIY EKVPIDLVCS FFDFFNIDIS 360
  361 PDQDYIKLNC 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.0
Match: 1dpiA
Description: STRUCTURE OF LARGE FRAGMENT OF ESCHERICHIA COLI DNA POLYMERASE I COMPLEXED WITH D/TMP
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle