YRC Public Data Repository - Protein Structure Prediction

Protein:	CE00184
Organism:	Caenorhabditis elegans
Length:	152 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE00184.

Description	E-value	Query Range	Subject Range
MSRB_THEEB - Peptide methionine sulfoxide reductase MsrB OS=Thermosynechococcus elongatus (strain BP-1) GN=msrB P... MSRB_SYNEL - Peptide methionine sulfoxide reductase msrB OS=Synechococcus elongatus GN=msrB PE=3 SV=1	238.0	[0..20]	[151..1]
gi\|75908017, gi\|... - gi\|75908017\|ref\|YP_322313.1\| methionine sulfoxide reductase B [Anabaena variabilis ATCC 29413], gi\|7...	236.0	[0..3]	[151..19]
gi\|86558601, gi\|... - gi\|86610059\|ref\|YP_478821.1\| methionine-R-sulfoxide reductase [Synechococcus sp. JA-2-3B'a(2-13)], g... gi\|86610059 - gi\|86610059\|ref\|YP_478821.1\| methionine-R-sulfoxide reductase [Cyanobacteria bacterium Yellowstone B...	235.0	[0..15]	[151..31]
gi\|60494275, gi\|... - gi\|60682841\|ref\|YP_212985.1\| bifunctional methionine sulfoxide reductase A/B protein [Bacteroides fr...	235.0	[0..6]	[152..198]
gi\|115368847, gi... - gi\|115374180\|ref\|ZP_01461467.1\| peptide methionine sulfoxide reductase MsrB [Stigmatella aurantiaca ...	233.0	[0..9]	[148..52]
gi\|17231393, gi\|... - gi\|17231393\|ref\|NP_487941.1\| methionine sulfoxide reductase B [Nostoc sp. PCC 7120], gi\|17133035\|dbj... gi\|25302990 - pir\|\|AF2293 hypothetical protein alr3901 [imported] - Nostoc sp. (strain PCC 7120)	233.0	[0..3]	[151..19]
gi\|111656942 - gi\|111656942\|ref\|ZP_01407760.1\| hypothetical protein SpneT_02001821 [Streptococcus pneumoniae TIGR4]	231.0	[0..12]	[152..216]
gi\|225724305, gi... - gi\|225856354\|ref\|YP_002737865.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pne... gi\|225722082, gi... - gi\|225858488\|ref\|YP_002739998.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pne... gi\|66879653 - gi\|66879653\|ref\|ZP_00404670.1\| COG0225: Peptide methionine sulfoxide reductase [Streptococcus pneumo... gi\|25508388 - gi\|25508388\|pir\|\|A97944 peptide methionine sulfoxide reductase homolog [imported] - Streptococcus pn... gi\|183569878, gi... - gi\|183569878\|gb\|EDT90406.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pneumoni... gi\|15902621, gi\|... - gi\|15902621\|ref\|NP_358171.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococcus ... gi\|147765199, gi... - gi\|149010718\|ref\|ZP_01832089.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococc... gi\|183572966, gi... - gi\|183572966\|gb\|EDT93494.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pneumoni... gi\|147762715, gi... - gi\|149005775\|ref\|ZP_01829514.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococc... gi\|168492265, gi... - gi\|183573518\|gb\|EDT94046.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pneumoni... gi\|147928857, gi... - gi\|148992231\|ref\|ZP_01821954.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococc... gi\|168996394, gi... - gi\|169833892\|ref\|YP_001694133.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pne... gi\|148989032, gi... - gi\|148989032\|ref\|ZP_01820432.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococc... gi\|182628920, gi... - gi\|182683586\|ref\|YP_001835333.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococ... gi\|194357165, gi... - gi\|194397498\|ref\|YP_002037316.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pne...	231.0	[0..12]	[152..216]
gi\|53714858, gi\|... - gi\|53714858\|ref\|YP_100850.1\| bifunctional methionine sulfoxide reductase A/B protein [Bacteroides fr...	231.0	[0..6]	[152..198]
gi\|240114037 - gi\|240114037\|ref\|ZP_04728527.1\| trifunctional thioredoxin/methionine sulfoxide reductase A/B protein... gi\|240015637 - gi\|240015637\|ref\|ZP_04722177.1\| trifunctional thioredoxin/methionine sulfoxide reductase A/B protein... MSRAB_NEIGO - Peptide methionine sulfoxide reductase MsrA/MsrB OS=Neisseria gonorrhoeae GN=msrAB PE=1 SV=2	231.0	[0..3]	[152..353]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTKKFRMED VGLSKLKVEK NPKDVKQTEW KSVLPNEVYR VARESGTETP HTGGFNDHFE  60
   61 KGRYVCLCCG SELFNSDAKF WAGCGWPAFS ESVGQDANIV RIVDRSHGMH RTEVRCKTCD 120
  121 AHLGHVFNDG PKETTGERYC INSVCMAFEK KD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.0
Match:	1l1dA
Description:	C-terminal MsrB domain of peptide methionine sulfoxide reductase PilB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor	5.90194589149201	bayes_pls_golite062009
protein-methionine-R-oxide reductase activity	5.64196103816384	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	3.02342037380774	bayes_pls_golite062009
peptide-methionine-(S)-S-oxide reductase activity	1.80676476343543	bayes_pls_golite062009
binding	1.67290562818139	bayes_pls_golite062009
catalytic activity	0.566791077255496	bayes_pls_golite062009
nucleic acid binding	0.555078494441175	bayes_pls_golite062009
ion binding	0.415760364192452	bayes_pls_golite062009
cation binding	0.404651661251597	bayes_pls_golite062009
metal ion binding	0.404651661251597	bayes_pls_golite062009
DNA binding	0.215568693193579	bayes_pls_golite062009
transcription regulator activity	0.183261590647643	bayes_pls_golite062009
protein binding	0.0755837372617499	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: