YRC Public Data Repository - Protein Structure Prediction

Protein:	cog4
Organism:	Schizosaccharomyces pombe
Length:	738 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cog4.

Description	E-value	Query Range	Subject Range
gi\|21070956, gi\|... - gi\|21070956\|ref\|NP_056201.1\| component of oligomeric golgi complex 4 [Homo sapiens], gi\|10434521\|dbj...	768.0	[0..5]	[738..33]
COG4_PONAB - Conserved oligomeric Golgi complex subunit 4 OS=Pongo abelii GN=COG4 PE=2 SV=1 gi\|55730952 - gi\|55730952\|emb\|CAH92194.1\| hypothetical protein [Pongo abelii]	764.0	[0..5]	[738..33]
gi\|57087315 - gi\|57087315\|ref\|XP_546836.1\| PREDICTED: similar to Conserved oligomeric Golgi complex component 4 is...	755.0	[0..5]	[738..36]
COG4_BOVIN - Conserved oligomeric Golgi complex subunit 4 OS=Bos taurus GN=COG4 PE=2 SV=1	754.0	[0..5]	[738..33]
gi\|109508109, gi... - gi\|157823399\|ref\|NP_001101919.1\| component of oligomeric golgi complex 4 [Rattus norvegicus], gi\|149...	742.0	[0..5]	[738..33]
COG4_MOUSE - Conserved oligomeric Golgi complex subunit 4 OS=Mus musculus GN=Cog4 PE=1 SV=1	738.0	[0..5]	[738..33]
gi\|114663498 - gi\|114663498\|ref\|XP_511080.2\| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]	726.0	[0..5]	[738..33]

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Predicted Domain #1

Region A:
Residues: [1-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDISINDCTD ISQIKQRFHD LQVESQRTDE KLERLLSDAQ PTEKFNSLIK NMAERLVLFV  60
   61 GQIEELKDAF CNTTIVSEEV IERIKSVDRE QNRIKECLLF VRQVRDFKEC LQDLNRAMHH 120
  121 QQWEKAADLV HRASSTSPAI IEGKFAHAVV PTAEQPLAPM DTLKEITESL HTLFWREFHK 180
  181 AARNQDQKEI TRYFKLFPLI GKEKEGLEAY WHFFGGIIAS KARATLDEPP THALFFAQAF 240
  241 TGLVEHVASI IRAHTPLVQK YYKAKNTITV IEKLQGDCDR QGSIIVNTMF DVRRIDNLVS 300
  301 SIASYKYILL HAKLKNR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1y1uA
Description:	Structure of unphosphorylated STAT5a
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [318-373]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFVSDQKELE RVSLQTLHPI LNEMSAIVSK WNISKIFISR LVLRLSQSDG TSNDPS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [374-738]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQDNLICASI FNSSKMELLL KKQLLPSLLQ LETYYFRRSI ETSLELEEYY TKVSPWMSSI  60
   61 VDDVMYVTKQ VFQRAFFTVS SLFFTRFVNE SLIPILRNDY YVYLSHNLLT VCNIIKAQFQ 120
  121 RLKNANSIPA KQVENYITLV NSASLSKQYL KSIVDGVSSR LEEVFAFAKD QKLVKKSIDN 180
  181 FLQLTVNFEN LCKTSFNMYF PIFLLPRIEQ CIDDSFDGIN YVLSYEDYTK ETEHERLVVT 240
  241 RLRSVWDRVL LLEQFTPENQ LSLRSMACEK AASYIENLIL YKIQWNDYGA MALENDISSL 300
  301 ITIFSNDQAN LRHSFERLQE ILILLVWESD STAPEQLIND LNLQLLSIDI VSAIMEKKAN 360
  361 VQGED

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.5
Match:	2fji1
Description:	No description for 2fji1 was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits