YRC Public Data Repository - Protein Structure Prediction

Protein:	trm13
Organism:	Schizosaccharomyces pombe
Length:	407 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for trm13.

Description	E-value	Query Range	Subject Range
CE22211 - status:Confirmed UniProt:Q9XW93 protein_id:CAA22074.1	321.0	[0..31]	[404..28]
gi\|114557883 - gi\|114557883\|ref\|XP_001160498.1\| PREDICTED: hypothetical protein isoform 4 [Pan troglodytes]	321.0	[0..31]	[402..31]
CCDC76 - coiled-coil domain containing 76	321.0	[0..31]	[402..31]
gi\|118780995, gi... - gi\|118780995\|ref\|XP_311210.3\| ENSANGP00000019057 [Anopheles gambiae str. PEST], gi\|116130211\|gb\|EAA0...	319.0	[0..31]	[405..29]
gi\|109011463 - gi\|109011463\|ref\|XP_001106928.1\| PREDICTED: similar to CG18048-PA [Macaca mulatta]	319.0	[0..31]	[402..31]
gi\|109467481, gi... - gi\|197927149\|ref\|NP_001029074.2\| coiled-coil domain containing 76 [Rattus norvegicus], gi\|183986268\|...	318.0	[0..31]	[403..31]
gi\|39589916, gi\|... - gi\|39589916\|emb\|CAE60914.1\| Hypothetical protein CBG04631 [Caenorhabditis briggsae], gi\|187035418\|em... gi\|157765166 - gi\|157765166\|ref\|XP_001674926.1\| Hypothetical protein CBG04631 [Caenorhabditis briggsae AF16]	317.0	[0..31]	[404..17]
TRM13_MOUSE - tRNA:m(4)X modification enzyme TRM13 homolog OS=Mus musculus GN=Trmt13 PE=2 SV=1	316.0	[0..31]	[403..31]

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Predicted Domain #1

Region A:
Residues: [1-106]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGNIRFLRK IAHLVQKTIK VVESLGLGWK QLVKKLSNLM ARIKKIFTQE ELKQIPCPYD  60
   61 HKHTIVRHRL EYHLKRCNAR PVERTDPYYK KDINISTSTD ASESSS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [107-407]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEIVDLSKEE LSKWICLFNR ISDSLPTPQK KVLFHPAMNA RLEEGTKKKH AIQQASLLGH  60
   61 MEKLHYFDNQ GSIYYEFGAG RAELSRYVQH CSQQENVYIL IDRDSNRTKH DSRILKDSIK 120
  121 NNWPEPKIIR CKIDIKDLKL DFFASEFRNS GKPVFAYSKH LCGAATDLTL NCLKSSPPNA 180
  181 LVIALCCHHH CRWRTLSTFA REQLSHWGIS NPQEFQILRQ MTGWAVNSLR EHMHASGGAD 240
  241 SHISGLSHEE RVKIGLKCKH IINYMRKLEC EKMGYESSLV YYVGEETTLE NVALIAYKRI 300
  301 N

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.04
Match:	1i1nA
Description:	Protein-L-isoaspartyl O-methyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	3.68431317301075	bayes_pls_golite062009
N-methyltransferase activity	3.64494850793256	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.60853685152199	bayes_pls_golite062009
protein methyltransferase activity	3.51986359093355	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.91374296950366	bayes_pls_golite062009
transferase activity	2.67612625778122	bayes_pls_golite062009
histone methyltransferase activity	2.666651371662	bayes_pls_golite062009
RNA methyltransferase activity	2.63941856307703	bayes_pls_golite062009
tRNA methyltransferase activity	2.21653466290591	bayes_pls_golite062009
DNA-methyltransferase activity	2.01680830778855	bayes_pls_golite062009
arginine N-methyltransferase activity	1.99340565364513	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	1.99340565364513	bayes_pls_golite062009
rRNA methyltransferase activity	1.85380504590369	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	1.64765900536818	bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity	1.54257365884902	bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity	1.54257365884902	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	1.27753381141602	bayes_pls_golite062009
catalytic activity	1.16970557486814	bayes_pls_golite062009
tRNA (adenine)-methyltransferase activity	0.966274102011523	bayes_pls_golite062009
tRNA (adenine-N1-)-methyltransferase activity	0.966274102011523	bayes_pls_golite062009
transcription regulator activity	0.953292160159369	bayes_pls_golite062009
DNA binding	0.878229880745235	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	0.735680462496249	bayes_pls_golite062009
nucleic acid binding	0.668500493633294	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.51222176401398	bayes_pls_golite062009
binding	0.486361285495359	bayes_pls_golite062009
RNA binding	0.413112349791396	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.338017594673896	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.286806504860858	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.113328595762489	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.0390774859535424	bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity	0.0180486171234466	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: