YRC Public Data Repository - Protein Structure Prediction

Protein:	edc3
Organism:	Schizosaccharomyces pombe
Length:	454 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for edc3.

Description	E-value	Query Range	Subject Range
gi\|44983500 - gi\|44983500\|gb\|AAS52636.1\| AEL049Wp [Ashbya gossypii ATCC 10895] gi\|44983500, gi\|... - gi\|45190558\|ref\|NP_984812.1\| AEL049Wp [Ashbya gossypii ATCC 10895], gi\|44983500\|gb\|AAS52636.1\| AEL04...	343.0	[0..3]	[432..1]
gi\|46122291, gi\|... - gi\|46122291\|ref\|XP_385699.1\| hypothetical protein FG05523.1 [Gibberella zeae PH-1], gi\|42551810\|gb\|E...	327.0	[0..38]	[434..200]
gi\|85081291 - gi\|85081291\|ref\|XP_956691.1\| hypothetical protein NCU00427 [Neurospora crassa OR74A] gi\|28917765, gi\|... - gi\|40882152\|emb\|CAF05979.1\| hypothetical protein [Neurospora crassa], gi\|32403800\|ref\|XP_322513.1\| h...	322.0	[0..29]	[434..222]
gi\|190405551 - gi\|190405551\|gb\|EDV08818.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] gi\|207346060 - gi\|207346060\|gb\|EDZ72672.1\| YEL015Wp-like protein [Saccharomyces cerevisiae AWRI1631] EDC3 - Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically ... EDC3_YEAST - Enhancer of mRNA-decapping protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EDC...	312.0	[0..3]	[432..1]
gi\|39940054, gi\|... - gi\|39940054\|ref\|XP_359564.1\| hypothetical protein MG05213.4 [Magnaporthe grisea 70-15], gb\|EAA52521....	308.0	[0..36]	[434..191]
gi\|46433588, gi\|... - gi\|68487871\|ref\|XP_712216.1\| hypothetical protein CaO19.14148 [Candida albicans SC5314], gi\|46433588... orf19.14148 - orf19.6858 CGDID:CAL0005806 Assembly 19, Contig19-20256 (42839, 41301) CDS, reverse complemented, tr...	306.0	[0..3]	[434..1]
gi\|76647266 - gi\|76647266\|ref\|XP_884056.1\| PREDICTED: hypothetical protein LOC517979 isoform 2 [Bos taurus]	303.0	[0..36]	[448..126]
gi\|74000745 - gi\|74000745\|ref\|XP_867080.1\| PREDICTED: similar to CG6311-PB isoform 2 [Canis familiaris]	300.0	[0..36]	[448..126]
EDC3_MACFA - Enhancer of mRNA-decapping protein 3 OS=Macaca fascicularis GN=EDC3 PE=2 SV=1	299.0	[0..36]	[448..126]

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Predicted Domain #1

Region A:
Residues: [1-158]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVADFYGSN VEVLLNNDSK ARGVITNFDS SNSILQLRLA NDSTKSIVTK DIKDLRILPK  60
   61 NEIMPKNGTK SPSTNSTKLK SAETYSSKNK WSMDCDEEFD FAANLEKFDK KQVFAEFREK 120
  121 DKKDPAKLLV SHNKSPNRNY HHKQNVLGPS VKDEFVDL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.06
Match:	1m5qA
Description:	Sm-Like archaeal protein Smap3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
	6.31759698998802	bayes_pls_golite062009
RNA binding	5.49978007278445	bayes_pls_golite062009
mRNA binding	2.42306415646781	bayes_pls_golite062009
nucleic acid binding	1.85673264747679	bayes_pls_golite062009
binding	1.34368822332546	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [159-454]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSAGSQINGI DAVLSSSSNG HVTPGSKKGS RETLKKKPFV DENIPAELHT TTGDILKPIT  60
   61 PEQLSQGIAL AIAKTSTDIV VENAAQLLSQ FVFSVLGGHK RLSSRNHNSQ PLVCILVGSH 120
  121 DHASAAVAAG RRLCAIGIKV VLRLLTPFNV DNRQLLMFQA AGGYIPTENF DQFLNKLTSP 180
  181 IELVVDVLTG FHPSIDKNSH ALIQWANDLN VLILSVDIPS GYTVQKKNTA ILPKWTLALG 240
  241 AVTTTLAQAA LVKQAAGVSV FVGNLGTGSQ TWAELGILES QVTGQYLAQI SCTSTN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.39794
Match:	2dg2A
Description:	No description for 2dg2A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: