YRC Public Data Repository - Protein Structure Prediction

Protein:	apl4
Organism:	Schizosaccharomyces pombe
Length:	865 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for apl4.

Description	E-value	Query Range	Subject Range
AP1G1_MOUSE - AP-1 complex subunit gamma-1 OS=Mus musculus GN=Ap1g1 PE=1 SV=3 gi\|227469 - gi\|227469\|prf\|\|1704251A gamma adaptin	552.0	[0..27]	[860..1]
gi\|189491695, gi... - gi\|189491695\|ref\|NP_604455.1\| adaptor-related protein complex 1, gamma 1 subunit [Rattus norvegicus]...	551.0	[0..27]	[860..1]
gi\|73957078, gi\|... - gi\|73957078\|ref\|XP_862646.1\| PREDICTED: similar to Adapter-related protein complex 1 gamma 1 subunit...	551.0	[0..27]	[860..1]
gi\|114663581, gi... - gi\|114663581\|ref\|XP_001171400.1\| PREDICTED: adaptor-related protein complex 1, gamma 1 subunit isofo... AP1G1 - adaptor-related protein complex 1, gamma 1 subunit	551.0	[0..27]	[860..1]
gi\|55732487 - gi\|55732487\|emb\|CAH92944.1\| hypothetical protein [Pongo abelii] AP1G1_PONAB - AP-1 complex subunit gamma-1 OS=Pongo abelii GN=AP1G1 PE=2 SV=1	550.0	[0..27]	[860..1]

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Predicted Domain #1

Region A:
Residues: [1-678]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTTHPKNLH LTCSGVERGF TNSPKTHPKM SSLKSFIKAV RASKTTAEEH TTILKESAQI  60
   61 RKNIRQGSND MRMRRKNVAK LLYLFLLGEP THFGQIECLK LLSSSRFMDK RLGYLAAMLL 120
  121 LDENQEVLTL LTNSLQNDLK SRDKFIVGLA LSAFGNVAGP ELARDLSNDI AELCSNHHNY 180
  181 ISKKAVLCAL RVIQKEPDLE SLYIEKTDEL LHSKSHGVLM AALAFAISAC KINPSLISRF 240
  241 ESQADDLIYR IRQLSTSTYS SEHNIGNISD PFLQVKILQF LSILGQNNPK IYDKMSDLLA 300
  301 QVCTNTDSSR NAGNAILYQA VRTILDLNSD SSLRVLGVNI LAKFLGNRDN NTRYVALNML 360
  361 KLVVNSEENA VQRHRSTILA CLNDVDSSIQ SRALELSTFL VNEANVRFMV RELLSFLDNV 420
  421 SDELRGSTAQ YITEVTNAFA PNKRWHFDTL LRVFKSAGNF VSESTLSTFL RLIASAPELH 480
  481 EYAVVKLYAA LKEDVSQEAL TLSAFWVIGE YGQMLLSPTM NFDDDQTLPH SVSESDIVDI 540
  541 IEEVFNSVEA SRYIIVQYGL FALTKLSARL GSSSTASRID KIIYSYKRNK NTEVQQRSVE 600
  601 FHLILNDSKL SKTILEPTPA PLPPPRTTPY QNAEQKLKAN KHVEKRVQES NELLDLIGLT 660
  661 TPSVAEPLET PVDEMTQS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	114.0
Match:	1w63A
Description:	AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [679-865]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSSLSRAPS TSKKSHFEDI LGLFASPAPS AQPVDSLASS FASLDFNASA SQPSNNLSLL  60
   61 SSIPSTSKSY PPIVVFDKHD VTLTLVPSKE ESTKTAVIEA KFKNKNPMTR VEKIHLEVAV 120
  121 PKSQKLKIQP LRTTSMEPGG ETSQTLRVHG PSGSQVKLRL RISVVRQGGS NTLDQVDFGK 180
  181 LPSDLLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.69897
Match:	1iu1A
Description:	Gamma1-adaptin domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	1.57801165255065	bayes_pls_golite062009
binding	1.4853299341494	bayes_pls_golite062009
transporter activity	1.4237388137024	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: