YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC10F6.04
Organism:	Schizosaccharomyces pombe
Length:	351 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC10F6.04.

Description	E-value	Query Range	Subject Range
gi\|50752803 - gi\|50752803\|ref\|XP_413753.1\| PREDICTED: similar to guanine nucleotide exchange factor p532 [Gallus g...	315.0	[0..2]	[344..374]
gi\|114657536, gi... - gi\|114657536\|ref\|XP_510467.2\| PREDICTED: guanine nucleotide exchange factor p532 isoform 2 [Pan trog...	313.0	[0..2]	[344..374]
gi\|62422573 - gi\|62422573\|ref\|NP_003913.2\| guanine nucleotide exchange factor p532 [Homo sapiens]	313.0	[0..2]	[344..374]
gi\|47212899 - gi\|47212899\|emb\|CAF90789.1\| unnamed protein product [Tetraodon nigroviridis]	312.0	[0..2]	[344..384]
gi\|5478530, gi\|1... - gi\|5478530\|gb\|AAD43920.1\|AF130441_1 UVB-resistance protein UVR8 [Arabidopsis thaliana], pir\|\|T50662 ...	311.0	[0..1]	[341..35]
gi\|109484871 - gi\|109484871\|ref\|XP_001075834.1\| PREDICTED: similar to guanine nucleotide exchange factor p532 [Ratt...	311.0	[0..2]	[344..374]
gi\|82922675, gi\|... - gi\|82922675\|ref\|XP_930567.1\| PREDICTED: similar to guanine nucleotide exchange factor p532 isoform 1...	311.0	[0..2]	[344..374]

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Predicted Domain #1

Region A:
Residues: [1-351]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLSLGSNGN FQLGLNNDED VYSPQIVPFD RAIEKISCGG NHTLLLDEDS QLWACGDNRK  60
   61 GQCGYEVKEP LYNPLSPDYL RIFTRVSHER WVFLTCGWEF SVIVHADRRR VCSCGEGLSG 120
  121 ELGQGNRSNS QGLREIDIPY LDDKEFIIDI SAGLRHWICV TNEGNLYGCG DGRKGQLGPV 180
  181 VMKTVNKVSF LGRIEHAQAV VCGVQFSAVL QETGHVIVLG GEKWNVAAEC DAWQANNSEL 240
  241 SSSICSISAN WSTLSLLSTE GCVYAFGRCD RAQKAHTKAS DIVQIASGTE HNILRTKKGS 300
  301 VLIYGWNEHG NASNDDKRDV YDAKTLQLPG WAYIVAAGYA TSWIVIEENH K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.522879
Match:	1a12A
Description:	Regulator of chromosome condensation RCC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.79978015066238	bayes_pls_golite062009
Ran guanyl-nucleotide exchange factor activity	1.12611051197363	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	1.05993294531818	bayes_pls_golite062009
GTPase regulator activity	1.03758696380346	bayes_pls_golite062009
ligase activity	0.957134518791255	bayes_pls_golite062009
guanyl-nucleotide exchange factor activity	0.947267197207143	bayes_pls_golite062009
small GTPase regulator activity	0.882132361980766	bayes_pls_golite062009
protein binding	0.775788303004353	bayes_pls_golite062009
Ras guanyl-nucleotide exchange factor activity	0.642436223706285	bayes_pls_golite062009
catalytic activity	0.261970921089142	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: