YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC417.11c
Organism:	Schizosaccharomyces pombe
Length:	435 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC417.11c.

Description	E-value	Query Range	Subject Range
GSA_HISS2 - Glutamate-1-semialdehyde 2,1-aminomutase OS=Histophilus somni (strain 2336) GN=hemL PE=3 SV=1	321.0	[0..25]	[431..3]
ARGD_THETN - Acetylornithine aminotransferase OS=Thermoanaerobacter tengcongensis GN=argD PE=3 SV=1 ARGD_CALS4 - Acetylornithine aminotransferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 1...	320.0	[0..42]	[430..7]
GSA_HAES1 - Glutamate-1-semialdehyde 2,1-aminomutase OS=Haemophilus somnus (strain 129Pt) GN=hemL PE=3 SV=1	319.0	[0..25]	[429..3]
ARGD_METJA - Acetylornithine aminotransferase OS=Methanocaldococcus jannaschii GN=argD PE=3 SV=1 ARGD_METJA - Acetylornithine aminotransferase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JA...	317.0	[0..42]	[431..12]
gi\|119524573, gi... - gi\|119719453\|ref\|YP_919948.1\| 4-aminobutyrate aminotransferase [Thermofilum pendens Hrk 5], gi\|11952...	317.0	[0..15]	[433..4]
gi\|76589160, gi\|... - gi\|76795352\|ref\|ZP_00777725.1\| Glutamate-1-semialdehyde-2,1-aminomutase:Siroheme synthase, N-termina... gi\|241903839, gi... - gi\|241903839\|ref\|ZP_04788556.1\| glutamate-1-semialdehyde-2,1-aminomutase [Thermoanaerobacter brockii...	316.0	[0..17]	[434..190]
gi\|109090867 - gi\|109090867\|ref\|XP_001082811.1\| PREDICTED: ornithine aminotransferase isoform 2 [Macaca mulatta]	316.0	[0..4]	[426..18]
gi\|134298152, gi... - gi\|88944090\|ref\|ZP_01147423.1\| Acetylornithine and succinylornithine aminotransferase [Desulfotomacu...	315.0	[0..34]	[426..4]
OAT - ornithine aminotransferase gi\|114633242, gi... - gi\|114633244\|ref\|XP_001135280.1\| PREDICTED: hypothetical protein isoform 4 [Pan troglodytes], gi\|114...	315.0	[0..4]	[426..18]

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Predicted Domain #1

Region A:
Residues: [1-435]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSEISDLSL AKEKSEAQFI ARNPKSNDFH CKACDSLPGG NTRTVLHGAP FPIFIEAGYG  60
   61 SKLRDVDGHE YTDFLNELTA GIYGHSNPVI KKALMQGFDE IGISLGGTTT CELNYAEALK 120
  121 SRFLSIEKIR FCNSGTEANI TAIIAARKFT GKRAVIAMHG GYHGGPLSFA HGISPYNMDS 180
  181 QDFILCEYNN STQFKELVNS SQDIAAVIVE AMQGAGGAIP ADKEFMQTIQ LECEKNDIVF 240
  241 ILDEVMTSRL SPGGLQQIYC LKPDLTTLGK YLGGGLPFGA FGGRADIMSC FDPRLPGSLS 300
  301 HSGTFNNDTL TLTAGYVGLT ELYTPEAVKR LNALGDGLRK DIESYCHNTK MSITGLGSIM 360
  361 NIHFTESGRV NSYNDTAGEV IELKDLLWMD LLKEGFWIAR RGMITLSLVL TESELEAFKL 420
  421 TIKAWIHRRM SLIRI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.221849
Match:	2gsaA
Description:	Glutamate-1-semialdehyde aminomutase (aminotransferase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-aminobutyrate transaminase activity	2.50008459801306	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
5-aminolevulinate synthase activity	1.85905571238884	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	1.56299344706732	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	1.56299344706732	bayes_pls_golite062009
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	1.4383564662931	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	1.29936025406628	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
transferase activity	0.737426388870721	bayes_pls_golite062009
intramolecular transferase activity, transferring amino groups	0.659071155545801	bayes_pls_golite062009
N-succinyltransferase activity	0.52897097514616	bayes_pls_golite062009
kynureninase activity	0.242752584041108	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: