YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC29B12.05c
Organism:	Schizosaccharomyces pombe
Length:	309 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC29B12.05c.

Description	E-value	Query Range	Subject Range
gi\|196113152, gi... - gi\|88796062\|ref\|ZP_01111746.1\| peptide release factor-glutamine N5-methyltransferase [Alteromonas ma...	196.0	[0..1]	[302..1]
gi\|20515121, gi\|... - gi\|20806671\|ref\|NP_621842.1\| rRNA or tRNA methylase [Thermoanaerobacter tengcongensis MB4], gi\|20515... gi\|20806671 - gi\|20806671\|ref\|NP_621842.1\| predicted rRNA or tRNA methylase [Thermoanaerobacter tengcongensis MB4]	188.0	[0..23]	[300..26]
PRMC_VIBF1 - Release factor glutamine methyltransferase OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=prmC P...	186.0	[0..6]	[301..8]
gi\|94427880, gi\|... - gi\|94500022\|ref\|ZP_01306557.1\| modification methylase, HemK family protein [Oceanobacter sp. RED65],...	185.0	[0..7]	[302..6]
gi\|28805730 - gi\|28805730\|dbj\|BAC59007.1\| HemK protein [Vibrio parahaemolyticus RIMD 2210633] gi\|28805730, gi\|... - gi\|28897518\|ref\|NP_797123.1\| HemK protein [Vibrio parahaemolyticus RIMD 2210633], gi\|28805730\|dbj\|BA...	183.0	[0..3]	[299..7]
gi\|14517939 - gi\|14517939\|gb\|AAK64442.1\|AF377339_3 protoporphyrinogen oxidase HemK [Myxococcus xanthus]	183.0	[0..2]	[302..7]
gi\|37525988, gi\|... - gi\|37525988\|ref\|NP_929332.1\| N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase [Photo...	183.0	[0..6]	[302..6]
gi\|108463432, gi... - gi\|108759552\|ref\|YP_633065.1\| putative protein methyltransferase HemK [Myxococcus xanthus DK 1622], ...	183.0	[0..2]	[302..7]
gi\|91228928, gi\|... - gi\|91228928\|ref\|ZP_01262826.1\| HemK protein [Vibrio alginolyticus 12G01], gi\|91187511\|gb\|EAS73845.1\|...	182.0	[0..3]	[299..7]
gi\|89952490, gi\|... - gi\|90022890\|ref\|YP_528717.1\| protein methyltransferase hemK [Saccharophagus degradans 2-40], gi\|8995...	182.0	[0..1]	[299..5]

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Predicted Domain #1

Region A:
Residues: [1-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLPRITKFA LYRENPCLLP LYHATRDPSL AKREWTWICK ELKLLYPEIS KHGLRKKIVN  60
   61 ACQLRARNYP LQYILKSQPF GNIKIDCQQG VLIPRWETEE WVERVVDKLN RLERLKPLKI 120
  121 LDLCTGSGCI SSFVLANLRV PHTIEAVDVS KKALKLAVKN CDRAIAHGTV GKINFHQIDV 180
  181 LNEHERVESL LQTSHVLLCN PPYISDDDFA AQTDISVRKY EPKLALLAKN GGNEFYYKFS 240
  241 QYIKRMLQRN AKDFVPLSLI VFEIGSTHQA KIVKSLFDDT NWQANIEQDG AHQDRVVIIT 300
  301 RKDRRLIDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.522879
Match:	1t43A
Description:	Crystal Structure Analysis of E.coli Protein (N5)-Glutamine Methyltransferase (HemK)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.25333584501255	bayes_pls_golite062009
transferase activity	1.07321114919891	bayes_pls_golite062009
transcription regulator activity	1.01607844066443	bayes_pls_golite062009
DNA binding	0.94293886328487	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.837368219068434	bayes_pls_golite062009
nucleic acid binding	0.731396842794323	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.644010137949015	bayes_pls_golite062009
methyltransferase activity	0.635463629299812	bayes_pls_golite062009
binding	0.546744797014504	bayes_pls_golite062009
N-methyltransferase activity	0.290696180200503	bayes_pls_golite062009
protein methyltransferase activity	0.197622476100051	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: