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View Structure Prediction Details

Protein: SPBC1347.13c
Organism: Schizosaccharomyces pombe
Length: 301 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC1347.13c.

Description E-value Query
Range
Subject
Range
gi|25316695 - pir||A83664 tRNA/rRNA methyltransferase BH0113 [imported] - Bacillus halodurans (strain C-125)
gi|15612676, gi|... - gi|15612676|ref|NP_240979.1| tRNA/rRNA methyltransferase [Bacillus halodurans C-125], gi|10172725|db...
226.0 [0..30] [299..2]
gi|77954715, gi|... - gi|77954715|ref|ZP_00819103.1| RNA methyltransferase TrmH, group 3 [Marinobacter aquaeolei VT8], gi|...
221.0 [0..31] [300..3]
gi|150015025, gi... - gi|82749273|ref|ZP_00911735.1| RNA methyltransferase TrmH, group 3 [Clostridium beijerincki NCIMB 80...
218.0 [0..3] [300..28]
gi|48892550, gi|... - gi|71674113|ref|ZP_00671860.1| RNA methyltransferase TrmH, group 3 [Trichodesmium erythraeum IMS101]...
218.0 [0..8] [299..9]
gi|86558795, gi|... - gi|86610253|ref|YP_479015.1| RNA methyltransferase [Synechococcus sp. JA-2-3B'a(2-13)], gi|86558795|...
gi|86610253 - gi|86610253|ref|YP_479015.1| RNA methyltransferase, TrmH family, group 3 [Cyanobacteria bacterium Ye...
217.0 [0..20] [299..94]
gi|52001802, gi|... - gi|52783952|ref|YP_089781.1| YacO [Bacillus licheniformis ATCC 14580], gi|52346454|gb|AAU39088.1| Ya...
217.0 [0..27] [299..1]
gi|114770938 - gi|114770938|ref|ZP_01448406.1| hypothetical protein OM2255_16034 [alpha proteobacterium HTCC2255]
gi|221133725 - gi|221133725|ref|ZP_03560030.1| 23S rRNA (guanosine-2'-O-)-methyltransferase [Glaciecola sp. HTCC299...
gi|114770938, gi... - gi|114770938|ref|ZP_01448406.1| hypothetical protein OM2255_16034 [alpha proteobacterium HTCC2255], ...
217.0 [0..27] [300..1]
gi|25316722 - pir||H97287 rRNA methylase, YACO B. subtilis ortholog [imported] - Clostridium acetobutylicum
gi|15026220, gi|... - gi|15896402|ref|NP_349751.1| rRNA methylase [Clostridium acetobutylicum ATCC 824], gi|15026220|gb|AA...
216.0 [0..27] [300..3]
gi|56908147, gi|... - gi|56961913|ref|YP_173635.1| tRNA/rRNA methyltransferase [Bacillus clausii KSM-K16], gi|56908147|dbj...
216.0 [0..21] [299..10]
gi|81300928, gi|... - gi|81300928|ref|YP_401136.1| RNA methyltransferase TrmH, group 3 [Synechococcus elongatus PCC 7942],...
215.0 [0..8] [299..218]

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Predicted Domain #1
Region A:
Residues: [1-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRSRVNLAR EVPKKAKAHL SKERRLIKED SEFVFGTHSV KNALATRKRE CRALYVQNAD  60
   61 IHSEFEEFLN KLQYKIPIKS VNKEHLNQIT ACRPHNGVVL EASSLNVPTI SDLLFPAGEE 120
  121 YNNKNGQDSP HNDLNEGKSS SSDNYPPLYV YVDGITDPQN MGAVIRSAYI LGAKGILLSK 180
  181 KHNTFLSPVV SKASAGALEV FNISHVKNPM VFLRNSVLKG WKVIGTKPAL PDNKDQIYTP 240
  241 HKIKTELMNE PKILVLGSEK GLRTNILTQC SHYVSIPGGD KYVDSLNVSV AAGILLYSLV 300
  301 N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.0
Match: 1gz0A
Description: RlmB, C-terminal domain; RlmB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA methyltransferase activity 4.23455016472464 bayes_pls_golite062009
methyltransferase activity 3.59960278169345 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.51722801996622 bayes_pls_golite062009
rRNA methyltransferase activity 3.14976989427746 bayes_pls_golite062009
tRNA methyltransferase activity 2.33123191403389 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.23755555119187 bayes_pls_golite062009
tRNA (guanine) methyltransferase activity 2.14623472760939 bayes_pls_golite062009
transferase activity 1.63934797352054 bayes_pls_golite062009
structural constituent of ribosome 1.0137045454994 bayes_pls_golite062009
catalytic activity 0.797300463760338 bayes_pls_golite062009
N-methyltransferase activity 0.736216022000293 bayes_pls_golite062009
structural molecule activity 0.694233763389628 bayes_pls_golite062009
binding 0.650146274744039 bayes_pls_golite062009
nucleic acid binding 0.404179021204849 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 0.319046095835882 bayes_pls_golite062009
0.16936231012632 bayes_pls_golite062009
snoRNA binding 0.155192244522672 bayes_pls_golite062009
protein binding 0.031057919963412 bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity 6.26422903788337E-4 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle