YRC Public Data Repository - Protein Structure Prediction

Protein:	sed5
Organism:	Schizosaccharomyces pombe
Length:	309 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sed5.

Description	E-value	Query Range	Subject Range
gi\|116193839, gi... - gi\|88182550\|gb\|EAQ90018.1\| hypothetical protein CHGG_06637 [Chaetomium globosum CBS 148.51], gi\|1161...	196.0	[0..37]	[309..47]
gi\|42548800, gi\|... - gi\|46130672\|ref\|XP_389116.1\| hypothetical protein FG08940.1 [Gibberella zeae PH-1], gi\|42548800\|gb\|E...	196.0	[0..2]	[309..5]
gi\|75859136, gi\|... - gi\|75859136\|ref\|XP_868908.1\| hypothetical protein AN9526.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	187.0	[0..2]	[309..5]
gi\|85118909 - gi\|85118909\|ref\|XP_965538.1\| hypothetical protein [Neurospora crassa OR74A] gi\|32417238, gi\|... - gi\|32417238\|ref\|XP_329097.1\| hypothetical protein [Neurospora crassa], gi\|28927348\|gb\|EAA36302.1\| hy...	184.0	[0..2]	[309..5]
gi\|109099266 - gi\|109099266\|ref\|XP_001111568.1\| PREDICTED: similar to syntaxin 2 isoform 2 [Macaca mulatta]	184.0	[0..47]	[308..131]
gi\|86196638, gi\|... - gi\|86196638\|gb\|EAQ71276.1\| hypothetical protein MGCH7_ch7g683 [Magnaporthe grisea 70-15], gi\|3997090...	184.0	[0..2]	[309..5]
gi\|32490453, gi\|... - gi\|83773236\|dbj\|BAE63363.1\| unnamed protein product [Aspergillus oryzae], gi\|32490453\|dbj\|BAC79150.1... gi\|169780064 - gi\|169780064\|ref\|XP_001824496.1\| hypothetical protein [Aspergillus oryzae RIB40]	182.0	[0..2]	[309..5]
gi\|113531728, gi... - gi\|9711872\|dbj\|BAB07966.1\| putative syntaxin of plants 31 [Oryza sativa Japonica Group], gi\|34906154... gi\|125524663 - gi\|125524663\|gb\|EAY72777.1\| hypothetical protein OsI_00640 [Oryza sativa Indica Group]	181.0	[0..2]	[308..10]
gi\|114196770, gi... - gi\|115385062\|ref\|XP_001209078.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	180.0	[0..2]	[309..5]
Syx5-PB, Syx5-PA - The gene Syntaxin 5 is referred to in FlyBase by the symbol Dmel\Syx5 (CG4214, FBgn0011708). It is a...	179.0	[0..1]	[294..158]

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Predicted Domain #1

Region A:
Residues: [1-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFQDRTAEF QACVTKTRSR LRTTTANQAV GGPDQTKHQK SEFTRIAQKI ANQINQTGEK  60
   61 LQKLSQLAKR KTLFDDRPVE IQELTFQIKQ SLSSLNSDIA SLQQVVKGNR NKPAQMNQHS 120
  121 ENVVVSLQNS LANTSMTFKD ILEIRTQNMK ASQNRTEKFV ASSSMNANPL INSGNSISPF 180
  181 ADYNDPKPEA NEDYLSLNLG DGANTRYEQM ALLESQTDTY SQQRMSSIQN IESTITELGG 240
  241 IFSQLAQMVS EQRETVQRID MHTDDIVSNI GSAQREIVKF YERMSSNRAL LFKIFGIVII 300
  301 FFLLWVLVT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.69897
Match:	1dn1B
Description:	Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
SNAP receptor activity	3.50393203740159	bayes_pls_golite062009
binding	2.61337814857056	bayes_pls_golite062009
protein transporter activity	2.305772311362	bayes_pls_golite062009
protein binding	1.82422117934251	bayes_pls_golite062009
phosphatidic acid binding	1.79882292156155	bayes_pls_golite062009
transporter activity	1.74189664015129	bayes_pls_golite062009
substrate-specific transporter activity	1.49085442233849	bayes_pls_golite062009
transmembrane transporter activity	1.13101548288086	bayes_pls_golite062009
SNARE binding	0.71459772253941	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.643064875848901	bayes_pls_golite062009
ion transmembrane transporter activity	0.370484918396857	bayes_pls_golite062009
channel activity	0.0647076360772156	bayes_pls_golite062009
passive transmembrane transporter activity	0.0647076360772156	bayes_pls_golite062009
substrate-specific channel activity	0.0435980899803177	bayes_pls_golite062009
phospholipid binding	0.0172309833091902	bayes_pls_golite062009
cytoskeletal protein binding	0.00476738027966683	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: