YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC22H12.03
Organism:	Schizosaccharomyces pombe
Length:	270 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC22H12.03.

Description	E-value	Query Range	Subject Range
gi\|214034777, gi... - gi\|254479271\|ref\|ZP_05092613.1\| hydrolase, alpha/beta fold family, putative [Carboxydibrachium pacif... gi\|20515541, gi\|... - gi\|20807053\|ref\|NP_622224.1\| alpha/beta superfamily hydrolase/acyltransferase [Thermoanaerobacter te... gi\|20807053 - gi\|20807053\|ref\|NP_622224.1\| predicted hydrolase or acyltransferase (alpha/beta hydrolase superfamil...	167.0	[0..1]	[268..4]
gi\|114619428 - gi\|114619428\|ref\|XP_001163565.1\| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 2 [Pan troglody...	167.0	[0..1]	[270..176]
gi\|148253777, gi... - gi\|78693761\|ref\|ZP_00858275.1\| non-heme chloroperoxidase (chloride peroxidase) (CPO-F) (chloroperoxi...	166.0	[0..2]	[270..55]
gi\|89085007, gi\|... - gi\|89100269\|ref\|ZP_01173135.1\| hydrolase, alpha/beta fold family protein [Bacillus sp. NRRL B-14911]...	165.0	[0..1]	[268..9]
gi\|83633852, gi\|... - gi\|83645809\|ref\|YP_434244.1\| alpha/beta superfamily hydrolase/acyltransferase [Hahella chejuensis KC...	165.0	[0..2]	[270..48]
gi\|78066438, gi\|... - gi\|78066438\|ref\|YP_369207.1\| Alpha/beta hydrolase [Burkholderia sp. 383], gi\|77967183\|gb\|ABB08563.1\|...	164.0	[0..2]	[269..6]
gi\|92393765, gi\|... - gi\|93006087\|ref\|YP_580524.1\| 3-oxoadipate enol-lactonase [Psychrobacter cryohalolentis K5], gi\|92393...	164.0	[0..6]	[269..10]

Back

Predicted Domain #1

Region A:
Residues: [1-270]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKPVKLAF EKYSATVAKH PPVLIFHGLL GSKRNWRSLA KKFSCKLDRD IYAIDQRCHG  60
   61 DSPCVAPLSY SAMALDAFQF MKDHKLDKAS IIGHSMGAKT AMVTALKWPD KVEKLVVVDN 120
  121 SPWYQDLPRD YGAYFRKMIQ IDEANITKYS EADKMMSTVE KDILVRSFLL SNLKKDSNNS 180
  181 NTFKFRVPIE LISKSLKTIE GFPASLNDLV YDSPTLVIRA LKAPFIPDSA LPVFKKFFPK 240
  241 YELVSLDCGH WVHFEKPKEF SESIINFLNN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.69897
Match:	1s8oA
Description:	Human soluble Epoxide Hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39629727416851	bayes_pls_golite062009
lipase activity	0.849473630399459	bayes_pls_golite062009
carboxylesterase activity	0.424330502936163	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.264183693934251	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: