YRC Public Data Repository - Protein Structure Prediction

Protein:	ape2
Organism:	Schizosaccharomyces pombe
Length:	882 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ape2.

Description	E-value	Query Range	Subject Range
gi\|9864149 - gi\|9864149\|gb\|AAG01326.1\|AF281863_1 aminopeptidase I [Schizosaccharomyces pombe]	808.0	[0..1]	[882..1]
gi\|169773399 - gi\|169773399\|ref\|XP_001821168.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83769029 - gi\|83769029\|dbj\|BAE59166.1\| unnamed protein product [Aspergillus oryzae]	799.0	[0..20]	[882..21]
gi\|32422353, gi\|... - gi\|32422353\|ref\|XP_331620.1\| hypothetical protein [Neurospora crassa], gi\|28920573\|gb\|EAA29936.1\| am... gi\|85091989 - gi\|85091989\|ref\|XP_959172.1\| aminopeptidase 2 [Neurospora crassa OR74A]	797.0	[0..20]	[881..22]
gi\|159125163 - gi\|159125163\|gb\|EDP50280.1\| aminopeptidase [Aspergillus fumigatus A1163] gi\|66849556, gi\|... - gi\|70994150\|ref\|XP_751922.1\| aminopeptidase [Aspergillus fumigatus Af293], gi\|66849556\|gb\|EAL89884.1...	795.0	[0..2]	[882..74]
gi\|68368751 - gi\|68368751\|ref\|XP_684042.1\| PREDICTED: similar to Aminopeptidase puromycin sensitive [Danio rerio]	795.0	[0..12]	[880..271]
gi\|114192682, gi... - gi\|115397799\|ref\|XP_001214491.1\| aminopeptidase 2 [Aspergillus terreus NIH2624], gi\|114192682\|gb\|EAU...	794.0	[0..20]	[882..21]
gi\|34873499, gi\|... - gi\|34873499\|ref\|XP_340890.1\| PREDICTED: similar to aminopeptidase puromycin sensitive [Rattus norveg...	789.0	[0..19]	[880..54]
Psa-PC - The gene Puromycin sensitive aminopeptidase is referred to in FlyBase by the symbol Dmel\Psa (CG1009...	788.0	[0..19]	[878..218]
gi\|62089422 - gi\|62089422\|dbj\|BAD93155.1\| membrane alanine aminopeptidase precursor variant [Homo sapiens]	788.0	[0..2]	[879..65]
gi\|74228873 - gi\|74228873\|dbj\|BAE21917.1\| unnamed protein product [Mus musculus]	788.0	[0..19]	[880..29]

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Predicted Domain #1

Region A:
Residues: [1-882]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVTIPKSTS KEDDKNRNLL PKNVKPIHYD LSLYPDLETF TYGGKVVVTL DVLEDSNSIT  60
   61 LHGINLRILT AALEWGSQTV WASEVSYGDE RIVLQFPSTV PANSVAVLTL PFTARISSGM 120
  121 EGFYRSSYVD SDGNTKYLAT TQMEPTSARR AFPCWDEPAL KATFTIDITA KENYTILSNM 180
  181 NAVEETVKDG LKTARFAETC RMSTYLLAWI VAELEYVEYF TPGKHCPRLP VRVYTTPGFS 240
  241 EQGKFAAELG AKTLDFFSGV FGEPYPLPKC DMVAIPDFEA GAMENWGLVT YRLAAILVSE 300
  301 DSAATVIERV AEVVQHELAH QWFGNLVTMQ FWDGLWLNEG FATWMSWFSC NHFYPEWKVW 360
  361 ESYVTDNLQS ALSLDALRSS HPIEVPIMHD YEINQIFDAI SYSKGSCVIR MVSKYVGEDT 420
  421 FIKGIQKYIS KHRYGNTVTE DLWAALSAES GQDISSTMHN WTKKTGYPVL SVSETNDGEL 480
  481 LIEQHRFLST GDVKPEEDTV IYWAPLKLKT MKDGKAVVDE KAVLSDRSKK IKVDKEALES 540
  541 YKLNSEQSGI YRVNYSADHL KKLSQIAVEK PDYLSVEDRA GLIADVASLS RAGYGKVSST 600
  601 LDLIKTWKDE PNFVVFAEML ARLNGIKSTL RFESSDIIAA MKKLVLEVSA TKAHSLGWEF 660
  661 KANDDHIIRQ FKSTVYNYAG LFGDDKVVKD ALSKFDAYAS GNKSAINDNL RSAVFNIAIR 720
  721 YGGAKSWDQL LEIYTKTNDP YVRNSCLRAF GVTEDEKYIQ KTLDLTLDPI VKEQDIYLIL 780
  781 VTLSTHKNGV LAMWKFATSN WDKLLSRLPV AGTMRGYVVR FVTSGFTHAS AIDKIKEFFA 840
  841 DKDTKLYERA LQQSLDTISA NSSFIDKSLD DITRWLKENR YM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	156.0
Match:	1z1wA
Description:	Crystal structures of the tricorn interacting facor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits