YRC Public Data Repository - Protein Structure Prediction

Protein:	snx3
Organism:	Schizosaccharomyces pombe
Length:	143 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for snx3.

Description	E-value	Query Range	Subject Range
gi\|40741178, gi\|... - gi\|67537256\|ref\|XP_662402.1\| hypothetical protein AN4798.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	146.0	[0..4]	[140..2]
gi\|60653701, gi\|... - gi\|60653703\|gb\|AAX29545.1\| sorting nexin 3 [synthetic construct], gi\|60653701\|gb\|AAX29544.1\| sorting...	143.0	[0..1]	[143..5]
gi\|114608755, gi... - gi\|55627184\|ref\|XP_518671.1\| PREDICTED: sorting nexin 3 isoform 5 [Pan troglodytes], gi\|114608755\|re... gi\|190402237 - gi\|190402237\|gb\|ACE77651.1\| sorting nexin 3 (predicted) [Sorex araneus] gi\|12850385, gi\|... - gi\|74208380\|dbj\|BAE26381.1\| unnamed protein product [Mus musculus], gi\|74185844\|dbj\|BAE32792.1\| unna... gi\|197215628 - gi\|197215628\|gb\|ACH53022.1\| sorting nexin 3 (predicted) [Otolemur garnettii] gi\|164449657 - gi\|164449657\|gb\|ABY56295.1\| sorting nexin 3 (predicted) [Papio anubis] SNX3 - sorting nexin 3 gi\|61361693, gi\|... - gi\|61361693\|gb\|AAX42088.1\| sorting nexin 3 [synthetic construct], gi\|190691283\|gb\|ACE87416.1\| sortin... gi\|226526922 - gi\|226526922\|gb\|ACO71280.1\| sorting nexin 3 (predicted) [Dasypus novemcinctus] gi\|166183799 - gi\|166183799\|gb\|ABY84161.1\| sorting nexin 3 (predicted) [Callithrix jacchus] gi\|149722861 - gi\|149722861\|ref\|XP_001504033.1\| PREDICTED: similar to Sorting nexin-3 (Protein SDP3) [Equus caballu... SNX3_BOVIN - Sorting nexin-3 OS=Bos taurus GN=SNX3 PE=2 SV=3 SNX3_PONAB - Sorting nexin-3 OS=Pongo abelii GN=SNX3 PE=2 SV=3 gi\|109073121, gi... - gi\|109073121\|ref\|XP_001094537.1\| PREDICTED: sorting nexin 3 isoform 4 [Macaca mulatta], gi\|109073119... gi\|169409579 - gi\|169409579\|gb\|ACA57921.1\| sorting nexin 3 (predicted) [Callicebus moloch] gi\|183637195 - gi\|183637195\|gb\|ACC64553.1\| sorting nexin 3 (predicted) [Rhinolophus ferrumequinum] SNX3_PONPY - Sorting nexin-3 - Pongo pygmaeus (Orangutan) gi\|217038307 - gi\|217038307\|gb\|ACJ76604.1\| sorting nexin 3 (predicted) [Oryctolagus cuniculus] gi\|55250822 - gb\|AAH86258.1\| Unknown (protein for MGC:98781) [Xenopus laevis] SNX3_RAT - Sorting nexin-3 OS=Rattus norvegicus GN=Snx3 PE=1 SV=1	143.0	[0..1]	[143..5]
gi\|114608757 - gi\|114608757\|ref\|XP_001148744.1\| PREDICTED: sorting nexin 3 isoform 2 [Pan troglodytes]	143.0	[0..1]	[143..5]
SNX3_MOUSE - Sorting nexin-3 OS=Mus musculus GN=Snx3 PE=1 SV=3	143.0	[0..1]	[143..5]
gi\|300676927\|gb\|... - PREDICTED: sorting nexin-3 isoform X1 [Zonotrichia albicollis], sorting nexin 3 [Zonotrichia albicol... gi\|197127399, gi... - gi\|197127400\|gb\|ACH43898.1\| putative sorting nexin 3 [Taeniopygia guttata], gi\|197127399\|gb\|ACH43897... gi\|53136422, gi\|... - gi\|57530297\|ref\|NP_001006408.1\| sorting nexin 3 [Gallus gallus], gi\|53136422\|emb\|CAG32540.1\| hypothe...	143.0	[0..1]	[143..5]
gi\|169146136, gi... - gi\|80751127\|ref\|NP_001032183.1\| sorting nexin 3 [Danio rerio], gi\|77748450\|gb\|AAI07639.1\| Sorting ne...	142.0	[0..1]	[143..5]
gi\|45360713, gi\|... - gi\|45360713\|ref\|NP_989030.1\| sorting nexin 12 [Xenopus (Silurana) tropicalis], gi\|38174116\|gb\|AAH614...	141.0	[0..1]	[143..5]

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Predicted Domain #1

Region A:
Residues: [1-143]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKLSRPEIR QQTTQQMYDV PENILEIDVI NPQTHGIGRN MFTTYEIVCR TNMPYFRLHN  60
   61 SSVRRRYSEF EKFHDMLERE SGRVSIPPLP GKIFTQRFRD DVIEERRQGL ENFLRLVAGH 120
  121 PLIQTHSRVL SSFLQSPEFK PTP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.09691
Match:	1ocsA
Description:	Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.88408675542289	bayes_pls_golite062009
protein binding	2.01416287650553	bayes_pls_golite062009
phosphoinositide binding	1.69611539954228	bayes_pls_golite062009
phospholipid binding	1.3509978234193	bayes_pls_golite062009
lipid binding	0.663652920263169	bayes_pls_golite062009
phosphatidylinositol-3-phosphate binding	0.643843925142106	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: