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View Structure Prediction Details

Protein: SPBC1683.11c
Organism: Schizosaccharomyces pombe
Length: 518 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC1683.11c.

Description E-value Query
Range		 Subject
Range
ACEA_CUCMA - Isocitrate lyase OS=Cucurbita maxima PE=2 SV=1
gi|1695645 - gi|1695645|dbj|BAA11320.1| Isocitrate Lyase [Cucurbita cv. Kurokawa Amakuri]
 639.0 [0..5] [515..11]
ACEA_GOSHI - Isocitrate lyase OS=Gossypium hirsutum PE=2 SV=1
 638.0 [0..5] [515..11]
ACEA_COCIM - Isocitrate lyase OS=Coccidioides immitis (strain RS) GN=ICL1 PE=2 SV=2
ACEA_COCIM - Isocitrate lyase OS=Coccidioides immitis GN=ICL1 PE=2 SV=2
 638.0 [0..1] [515..1]
ACEA_EMENI - Isocitrate lyase OS=Emericella nidulans GN=acuD PE=1 SV=3
ACEA_EMENI - Isocitrate lyase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)...
 635.0 [0..5] [515..4]
gi|68210 - pir||WZCSI isocitrate lyase (EC 4.1.3.1) - castor bean
ACEA_RICCO - Isocitrate lyase OS=Ricinus communis PE=2 SV=1
 634.0 [0..5] [515..11]
gi|85691195, gi|... - gi|85691195|gb|ABC73716.1| probable methyl isocitrate lyase [Aspergillus niger], gi|134055462|emb|CA...
gi|145230077 - gi|145230077|ref|XP_001389347.1| hypothetical protein An01g09270 [Aspergillus niger]
 633.0 [0..5] [515..4]
ACEA_BRANA - Isocitrate lyase OS=Brassica napus PE=2 SV=1
 632.0 [0..5] [515..11]
ACEA_CUCSA - Isocitrate lyase OS=Cucumis sativus PE=3 SV=1
 632.0 [0..5] [515..11]
gi|418804 - gi|418804|pir||S26857 isocitrate lyase (EC 4.1.3.1) - Emericella nidulans
 631.0 [0..5] [515..4]

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Predicted Domain #1
Region A:
Residues: [1-518] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTDMDLEQL EYEKEVEEIE KWWATPKQSQ IKRPYTASTV AVLSEVTKAY YPSSQQALKL  60
   61 YDLLREHRNK GTATLTYGVV DPVLASQASK AGLETIFVSG CLCGLSSVDE PGMDHADYPW 120
  121 DTVPKAVDRI FRSQNWHARR QKQFHLMKPA EERKQLPKYD YLLPIIADGD MGFGSVTSTM 180
  181 KMTKRFVESG VAMIHLDDLA IGLKRFTVGQ GRTVVPTSEY LRRLTAVRLQ FDIMKAETML 240
  241 LCRCDTDHAE FITSVVDPRD HAYVLGATTK IESLIKALKD AESTGVSMKK ARENWIERAK 300
  301 LMTFDEAVKS TATPKEYENY ISAISKKPFH SISERQELAE KYLSNEVFFD WELPRSSDGQ 360
  361 YFFKPTVQTV IERAIAAAPL GEMTWARMDY PKWQDIKAFH EGVRAVYPDR MFAFGFTGNY 420
  421 DFKAAGFSEE QLRNLTSDMA KLGVCWQVQP YFTCQVLNKA SVDYSNIWKK DGIFGYVKTV 480
  481 QEPALKEDVD GFENEWCGTY FADKLLSAAG SSDKTIPY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1dquA
Description: Isocitrate lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
isocitrate lyase activity 4.96824258511407 bayes_pls_golite062009
methylisocitrate lyase activity 4.21728284668468 bayes_pls_golite062009
catalytic activity 2.59838799615646 bayes_pls_golite062009
transferase activity 1.07154136609184 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.366715189574293 bayes_pls_golite062009
lyase activity 0.0456521871650777 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle