YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC6F6.11c
Organism:	Schizosaccharomyces pombe
Length:	309 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC6F6.11c.

Description	E-value	Query Range	Subject Range
gi\|110802744, gi... - gi\|110802744\|ref\|YP_698658.1\| phosphomethylpyrimidine kinase [Clostridium perfringens SM101], gi\|110...	202.0	[0..1]	[285..1]
gi\|149948927, gi... - gi\|77686688\|ref\|ZP_00802021.1\| Phosphomethylpyrimidine kinase [Alkaliphilus metalliredigenes QYMF], ...	201.0	[0..4]	[285..1]
gi\|110674810, gi... - gi\|110800163\|ref\|YP_695988.1\| phosphomethylpyrimidine kinase [Clostridium perfringens ATCC 13124], g...	199.0	[0..1]	[285..1]
gi\|18145000, gi\|... - gi\|18310320\|ref\|NP_562254.1\| phosphomethylpyrimidine kinase [Clostridium perfringens str. 13], gi\|18...	199.0	[0..1]	[285..1]
PDXK_SHEEP - Pyridoxal kinase OS=Ovis aries GN=PDXK PE=1 SV=1	198.0	[0..1]	[305..1]
PDXK_BOVIN - Pyridoxal kinase OS=Bos taurus GN=PDXK PE=2 SV=1	198.0	[0..1]	[305..1]
gi\|106895590, gi... - gi\|158321715\|ref\|YP_001514222.1\| phosphomethylpyrimidine kinase [Alkaliphilus oremlandii OhILAs], gi...	198.0	[0..4]	[283..1]
gi\|28211403, gi\|... - gi\|28211403\|ref\|NP_782347.1\| hydroxymethylpyrimidine kinase [Clostridium tetani E88], gi\|28203844\|gb...	197.0	[0..3]	[287..6]
gi\|110591348, gi... - gi\|110591348\|pdb\|2F7K\|B Chain B, Crystal Structure Of Human Pyridoxal Kinase, gi\|110591347\|pdb\|2F7K\|...	197.0	[0..1]	[305..16]
gi\|109065178 - gi\|109065178\|ref\|XP_001104678.1\| PREDICTED: pyridoxal kinase isoform 2 [Macaca mulatta]	196.0	[0..1]	[305..1]

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Predicted Domain #1

Region A:
Residues: [1-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTTKRILAI QSSVCHGYVG NRAATFPLQL LGWDVDAIPT VELSNHAGYP IVKGRTLSAE  60
   61 QILDLYKGVS AANPSGYECL LTGYARGIGS VKAIMEIVRS VKSKNKKAFW VFDPVLGDNG 120
  121 RLYVEESIIP LYREMLPFAD LITPNGFEAE ILSGMRINSI DTAFKCVECL QQKYKVPRVV 180
  181 ISSFVVEENG VEKLYCIGSS IYSKSFFVLI PVIPGIFRGT GDLFTALMAA HIAESPDCTE 240
  241 SLASIKEDKL KKSVEMALSS VHEVIQKTAD RISALGVEEY HPAYAELCIV NSQNSIIAPS 300
  301 KLFEAVYYY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.0
Match:	1lhpA
Description:	Pyridoxal kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	3.96411195020495	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	3.67035256855428	bayes_pls_golite062009
transferase activity	3.30865420017814	bayes_pls_golite062009
lithium ion binding	3.00550221878163	bayes_pls_golite062009
sodium ion binding	2.93046843966773	bayes_pls_golite062009
pyridoxal kinase activity	2.62798458074822	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.56927916030784	bayes_pls_golite062009
phosphomethylpyrimidine kinase activity	2.12104666683074	bayes_pls_golite062009
pyridoxal binding	2.04719269680858	bayes_pls_golite062009
catalytic activity	1.74474587246986	bayes_pls_golite062009
binding	1.4216897826135	bayes_pls_golite062009
carbohydrate kinase activity	1.32862180479506	bayes_pls_golite062009
nucleic acid binding	1.23363144435362	bayes_pls_golite062009
transcription regulator activity	1.21529398967164	bayes_pls_golite062009
potassium ion binding	1.18018952731159	bayes_pls_golite062009
alkali metal ion binding	1.18018952731159	bayes_pls_golite062009
DNA binding	0.954497955488766	bayes_pls_golite062009
transcription factor activity	0.376784274163604	bayes_pls_golite062009
protein binding	0.117280046908929	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: