YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC8E11.04c
Organism:	Schizosaccharomyces pombe
Length:	224 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC8E11.04c.

Description	E-value	Query Range	Subject Range
gi\|39795561, gi\|... - gi\|45361419\|ref\|NP_989287.1\| hypothetical protein LOC394905 [Xenopus (Silurana) tropicalis], gi\|3979...	158.0	[0..1]	[222..6]
gi\|50737613 - gi\|50737613\|ref\|XP_419203.1\| PREDICTED: similar to Acyl-protein thioesterase 1 (Lysophospholipase I)...	158.0	[0..1]	[222..6]
gi\|148225532, gi... - gi\|27881717\|gb\|AAH44315.1\| MGC52664 protein [Xenopus laevis], gi\|148225532\|ref\|NP_001079559.1\| simil...	156.0	[0..1]	[222..6]
gi\|41152185, gi\|... - gi\|41152185\|ref\|NP_957043.1\| lysophospholipase II [Danio rerio], gi\|37748063\|gb\|AAH59556.1\| Zgc:7321...	154.0	[0..1]	[222..6]
gi\|109086409 - gi\|109086409\|ref\|XP_001083287.1\| PREDICTED: lysophospholipase I isoform 2 [Macaca mulatta]	153.0	[0..1]	[222..6]
LYPA1_PONPY - Acyl-protein thioesterase 1 - Pongo pygmaeus (Orangutan) LYPA1_PONAB - Acyl-protein thioesterase 1 OS=Pongo abelii GN=LYPLA1 PE=2 SV=1	153.0	[0..1]	[222..6]
gi\|123996083, gi... - gi\|123996083\|gb\|ABM85643.1\| lysophospholipase I [synthetic construct], gi\|123981248\|gb\|ABM82453.1\| l... LYPLA1 - lysophospholipase I	153.0	[0..1]	[222..6]

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Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAKLNSVII NPSVAHTATV IFLHGLGDSG QGWSFMANTW SNFKHIKWIF PNAPSIPVTV  60
   61 NNGMKMPAWY DIYSFADMKR EDENGILRSA GQLHELIDAE LALGIPSDRI LIGGFSQGCM 120
  121 VSLYAGLTYP KRLAGIMGHS GFLPLASKFP SALSRVAKEI PILLTYMTED PIVPSVLSSA 180
  181 SAKYLINNLQ LKCLDRPFEG DAHSLSSESF MAMYKFTQTV IGSP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.69897
Match:	1fj2A
Description:	Acyl protein thioesterase 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.75934962198703	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.09488027320166	bayes_pls_golite062009
lipase activity	0.849473630399459	bayes_pls_golite062009
carboxylesterase activity	0.424330502936163	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: