YRC Public Data Repository - Protein Structure Prediction

Protein:	iws1
Organism:	Schizosaccharomyces pombe
Length:	428 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for iws1.

Description	E-value	Query Range	Subject Range
gi\|12840232 - gi\|12840232\|dbj\|BAB24793.1\| unnamed protein product [Mus musculus]	291.0	[0..171]	[428..4]
gi\|114580777 - gi\|114580777\|ref\|XP_001139705.1\| PREDICTED: hypothetical protein [Pan troglodytes]	290.0	[0..2]	[428..633]
gi\|76609295, gi\|... - gi\|76609295\|ref\|XP_883756.1\| PREDICTED: similar to CG9915-PA isoform 6 [Bos taurus], gi\|76609293\|ref...	288.0	[0..157]	[428..5]
gi\|7023152 - gi\|7023152\|dbj\|BAA91858.1\| unnamed protein product [Homo sapiens]	287.0	[0..157]	[428..5]
gi\|50751905 - gi\|50751905\|ref\|XP_422571.1\| PREDICTED: similar to hypothetical protein 3000008H23 [Gallus gallus]	272.0	[0..145]	[428..6]
gi\|54643421, gi\|... - gi\|54643421\|gb\|EAL32165.1\| GA22119-PA [Drosophila pseudoobscura], gi\|125982527\|ref\|XP_001355109.1\| G...	268.0	[0..132]	[428..212]
gi\|41581304, gi\|... - gi\|41581304\|emb\|CAE47953.1\| hypothetical protein, conserved [Aspergillus fumigatus], gi\|19309406\|emb...	260.0	[0..7]	[416..2]

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Predicted Domain #1

Region A:
Residues: [1-142]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEEKAELE NMQVESEAKT SENDQTIDTK VDVADVTTHV DEDLDNKEEA LDFSEDELSD  60
   61 LDENQFENFD ESKIGREAEE PTIYNLPTFK KKQEPNTIEE NLEVPRKVRK EQKPRRRRGK 120
  121 RSSTVDALND ELNELGENEE EV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [143-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTEQKQLDPT LAAKKELDLQ MDAVLKPTRT KKRSNEDNLE QMADDEVLRL REQMRLAALR  60
   61 DAELNSEQLP ATEKLKMLPL VDAVLRKTHL YDTILDN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [240-319]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVLDSVRMWL EPLPDRSLPA LNIQRSLMDI LTKLPIQTEH LRESKIGRIV LFYTISKKPE  60
   61 PFIKRIADNL VSEWSRPIIK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.23
Match:	1eo0A
Description:	Transcription elongation factor TFIIS N-domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [320-428]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSANYRDRAV GVASFNPEVF QTRRRRDLAA AESNDDAQAS RTGRTVIPRS IDSRYQVAPR  60
   61 VRLNPTAMTI AGRMKPADTE QVRKLKAKMK AIRSKSSKKS GVSIEGRGL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits