YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC25B8.09
Organism:	Schizosaccharomyces pombe
Length:	251 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC25B8.09.

Description	E-value	Query Range	Subject Range
YL8A_SCHPO - Uncharacterized methyltransferase-like C25B8.10 OS=Schizosaccharomyces pombe (strain 972 / ATCC 2484... SPAC25B8.10 - trans-aconitate 3-methyltransferase	154.0	[0..6]	[249..10]
gi\|90331572, gi\|... - gi\|90416819\|ref\|ZP_01224749.1\| probable biotin synthesis protein BioC [marine gamma proteobacterium ... gi\|90416819\|ref\|... - probable biotin synthesis protein BioC [marine gamma proteobacterium HTCC2207]	150.0	[0..2]	[247..281]
gi\|78364606, gi\|... - gi\|78486320\|ref\|YP_392245.1\| biotin biosynthesis protein BioC [Thiomicrospira crunogena XCL-2], gi\|7...	149.0	[0..2]	[249..9]
gi\|90324431, gi\|... - gi\|90414523\|ref\|ZP_01222498.1\| putative biotin synthesis protein BioC [Photobacterium profundum 3TCK...	144.0	[0..2]	[244..28]
gi\|94501347, gi\|... - gi\|94501347\|ref\|ZP_01307867.1\| biotin synthesis protein BioC [Oceanobacter sp. RED65], gi\|94426460\|g...	143.0	[0..2]	[248..7]
gi\|77383111, gi\|... - gi\|77459108\|ref\|YP_348614.1\| hypothetical protein Pfl01_2883 [Pseudomonas fluorescens Pf0-1], gi\|773...	142.0	[0..6]	[249..13]
gi\|46913930, gi\|... - gi\|54309494\|ref\|YP_130514.1\| putative biotin synthesis protein BioC [Photobacterium profundum SS9], ...	142.0	[0..2]	[244..28]
MENG_STAA1 - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) GN=menG PE... MENG_STAAW - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain MW2) GN=menG PE=3 SV=1 MENG_STAAE - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain Newman) GN=menG PE=3 SV=1 MENG_STAA9 - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain JH9) GN=menG PE=3 SV=1 gi\|269203096\|ref... - ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcus aureus subsp. aureus ED98] gi\|25304996 - pir\|\|G89925 menaquinone biosynthesis methyltransferase [imported] - Staphylococcus aureus (strain N3... MENG_STAAT - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain USA300 / TCH1516) GN=menG PE=... gi\|221140962 - gi\|221140962\|ref\|ZP_03565455.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... MENG_STAAS - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain MSSA476) GN=menG PE=3 SV=1 gi\|221138325 - gi\|221138325\|ref\|ZP_03563127.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... MENG_STAAM - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=menG P... MENG_STAAN - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain N315) GN=menG PE=1 SV=1 gi\|251802063, gi... - gi\|251814398\|ref\|ZP_04828871.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|253315978 - gi\|253315978\|ref\|ZP_04839191.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|253732113, gi... - gi\|253732113\|ref\|ZP_04866278.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|253728822, gi... - gi\|253733282\|ref\|ZP_04867447.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|255006257 - gi\|255006257\|ref\|ZP_05144858.2\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... MENG_STAA2 - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain JH1) GN=menG PE=3 SV=1 MENG_STAAC - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain COL) GN=menG PE=3 SV=1	141.0	[0..2]	[183..11]
MENG_STAAB - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) GN=menG...	140.0	[0..2]	[183..11]
gi\|89094132, gi\|... - gi\|89094132\|ref\|ZP_01167075.1\| biotin synthesis protein BioC [Oceanospirillum sp. MED92], gi\|8908160...	139.0	[0..2]	[247..10]

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Predicted Domain #1

Region A:
Residues: [1-251]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGRTFKTDI ADYETARPDY PPQITEWLND EFSVNETSTI LELGAGSGKL TPRIIASQPK  60
   61 EIIAVDTYVE MLDVLKKKFP NVDCRVGSAM AIPLEDESVD LVACGQCFHW FANEEALKEI 120
  121 YRVLKPNGKL ALIWNIRDNS VPWVEKCSQL LEKCRGGPLN MFEKAAELFP GYGFTELKQS 180
  181 LFTSAKKYSI EDLHRLMNSF SSINRLPVEE KEKMHAELDE IIKTIPRAQN TDQVDFNILT 240
  241 VAYSSEKVPI N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.30103
Match:	1vl5A
Description:	Crystal structure of hypothetical protein (BH2331) from Bacillus halodurans at 1.95 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity	1.77671966857605	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.644010137949015	bayes_pls_golite062009
methyltransferase activity	0.635463629299812	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.181420092548185	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: