YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC337.11
Organism:	Schizosaccharomyces pombe
Length:	325 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC337.11.

Description	E-value	Query Range	Subject Range
gi\|40795502 - gi\|40795502\|gb\|AAR91477.1\| thermostable alcohol dehydrogenase [Geobacillus sp. M10EXG]	259.0	[0..7]	[325..1]
ADH3_GEOSE - Alcohol dehydrogenase OS=Geobacillus stearothermophilus PE=1 SV=1	256.0	[0..7]	[324..1]
gi\|86134306, gi\|... - gi\|86134306\|ref\|ZP_01052888.1\| zinc-binding dehydrogenase [Polaribacter sp. MED152], gi\|85821169\|gb\|...	254.0	[0..7]	[322..12]
gi\|56961828, gi\|... - gi\|56961828\|ref\|YP_173550.1\| alcohol dehydrogenase [Bacillus clausii KSM-K16], gi\|56908062\|dbj\|BAD62...	252.0	[0..2]	[322..5]
gi\|75812768, gi\|... - gi\|75812768\|ref\|YP_320385.1\| zinc-containing alcohol dehydrogenase superfamily protein [Anabaena var...	252.0	[0..5]	[325..319]
ADH2 - Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; i... ADH2_YEAST - Alcohol dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH2 PE=1 SV=3	251.0	[0..1]	[323..1]
gi\|37787875 - gi\|37787875\|gb\|AAP51051.1\| alcohol dehydrogenase 2 [Saccharomyces pastorianus] YMR303C.ADH2_273... - null, null, null, null, null, null, null, null, null	251.0	[0..1]	[323..1]
gi\|56419266, gi\|... - gi\|56419266\|ref\|YP_146584.1\| alcohol dehydrogenase [Geobacillus kaustophilus HTA426], gi\|56379108\|db...	251.0	[0..7]	[322..1]
gi\|222055606, gi... - gi\|222055606\|ref\|YP_002537968.1\| Alcohol dehydrogenase zinc-binding domain protein [Geobacter sp. FR...	251.0	[0..2]	[322..1]

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Predicted Domain #1

Region A:
Residues: [1-325]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQYYQMMKAL RMLKKPKPGC LGIEIQSVPI PQPKNGELLV KIEAAAINPS DLMNATGGFP  60
   61 YTVYPRIVGR DYAGTVISGA SHLVGTRVFG TSGSELSFTK DGTHAEYCII PEKAAVRMPS 120
  121 NLSFTEAASV GVPFTTAYLA LSRGETKGSD IVLVVGALGA VGSAVCQIAE DWGCKVITVS 180
  181 RSGSTDINTV VDPELKRVHE LVEKVDVVID TVGDPLLMKS ALNQLGIGGR LSYISAPKQG 240
  241 SIEFSYDMKQ IYRKNLKIIG CNSLLLSLVE SNSLLKNMVA KFEAGKYKVL NKKIAETSLT 300
  301 DECINSYRKL MNECSTKFVI TMSTN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.30103
Match:	1rjwA
Description:	CRYSTAL STRUCTURE OF NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE FROM BACILLUS STEAROTHERMOPHILUS STRAIN LLD-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	2.38343643417648	bayes_pls_golite062009
binding	1.57459853671728	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.30535930879645	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	1.22416351603098	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.22202241547461	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	0.861534636764975	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.576163737662951	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	0.558610278939188	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.51503848775098	bayes_pls_golite062009
protein binding	0.417403352171849	bayes_pls_golite062009
catalytic activity	0.217171374336363	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.0913823272876781	bayes_pls_golite062009
chaperone binding	0.0748751300531033	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: