YRC Public Data Repository - Protein Structure Prediction

Protein:	cid12
Organism:	Schizosaccharomyces pombe
Length:	336 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cid12.

Description	E-value	Query Range	Subject Range
gi\|94385311 - gi\|94385311\|ref\|XP_994210.1\| PREDICTED: similar to PAP associated domain containing 5 (Topoisomerase...	250.0	[0..15]	[328..123]
gi\|50753709 - gi\|50753709\|ref\|XP_414098.1\| PREDICTED: similar to hypothetical protein [Gallus gallus]	249.0	[0..18]	[328..772]
gi\|109508506 - gi\|109508506\|ref\|XP_001066974.1\| PREDICTED: similar to PAP associated domain-containing 5 (Topoisome...	249.0	[0..20]	[287..277]
gi\|22831959, gi\|... - gi\|45554563\|ref\|NP_996383.1\| CG11265-PB, isoform B [Drosophila melanogaster], gi\|45554556\|ref\|NP_996...	243.0	[0..11]	[328..262]
gi\|73950408 - gi\|73950408\|ref\|XP_535307.2\| PREDICTED: similar to PAP associated domain containing 5 (Topoisomerase...	242.0	[0..20]	[287..142]

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Predicted Domain #1

Region A:
Residues: [1-336]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKVLLELHS VPWNEEGLSD NARLYSFLEF VSPKIEELKY RKLLLEKLQT HIREVVLDAE  60
   61 LQVYGSMYIG TTLSISDVDV SLKSPRVGEL EKRRVTMVLR KYLDADADFH SSARVPRINL 120
  121 VDVSGIGVDL TFGNDKACRT AELQKAYNEE HPIFGRLLML LKHWLFERDL ENVHHGGIAS 180
  181 CALSYMLIGW LEMRFHKKGI DSEVQPIRAL LQKFFYFWGV EWTYELFVLR PLTGQIVPKL 240
  241 QKGWLNEVQP NLLSIEDPID RNNDIGKQSF QISMIKAAFV ASANELLSDK TWFSTFAITE 300
  301 DEMFLCKQFE NVINTKRSLV EGYDSDTESD ELQAGG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.0
Match:	1f5aA
Description:	Poly(A) polymerase, middle domain; Poly(A) polymerase N-terminal, catalytic domain; Poly(A) polymerase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleotidyltransferase activity	6.98311287327254	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	5.66611091580726	bayes_pls_golite062009
transferase activity	4.39508042323068	bayes_pls_golite062009
RNA binding	3.35578898341041	bayes_pls_golite062009
nucleic acid binding	2.53528619920768	bayes_pls_golite062009
DNA binding	1.92558226050462	bayes_pls_golite062009
polynucleotide adenylyltransferase activity	1.54779952898232	bayes_pls_golite062009
binding	1.48092751553298	bayes_pls_golite062009
catalytic activity	0.75232920999699	bayes_pls_golite062009
cytoskeletal protein binding	0.374635535973312	bayes_pls_golite062009
transcription factor binding	0.303837517417996	bayes_pls_golite062009
protein binding	0.117945573723438	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: